Purdue at Michigan State odds, picks and predictions

Analyzing Friday’s Purdue at Michigan State odds and lines, with college football expert picks, predictions and best bets.

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The Purdue Boilermakers (1-9, 0-7 Big Ten) visit the Michigan State Spartans (4-6, 2-5) on Friday. Kickoff from Spartan Stadium is scheduled for 8 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s college football odds around the Purdue vs. Michigan State odds, and make our expert college football picks and predictions.

Purdue has dropped 9 games in a row after losing 49-10 against the Penn State Nittany Lions on Saturday and failing to cover as a 30-point home underdog. QB Hudson Card went 11-of-20 for 151 yards in the loss.

Michigan State has lost 3 straight games, the last a 38-16 setback against the Illinois Fighting Illini on Saturday and failing to cover as a 1.5-point road underdog. QB Aidan Chiles went 23-of-40 for 256 yards with 2 TDs while also leading the team with 40 rushing yards in the loss.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Purdue at Michigan State odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Thursday at 11:41 p.m. ET.

  • Moneyline (ML): Purdue +400 (bet $100 to win $400) | Michigan State -550 (bet $550 to win $100)
  • Against the spread (ATS): Purdue +13.5 (-105) | Michigan State -13.5 (-115)
  • Over/Under (O/U): 48.5 (O: -110 | U: -110)

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Purdue at Michigan State picks and predictions

Prediction

Michigan State 24, Purdue 9

Moneyline

PASS.

There is no value on Michigan State (-550) to beat a struggling Purdue (+400) team that has lost 9 straight games, 7 of them by double digits.

Against the spread

BET MICHIGAN STATE -13.5 (-110).

Purdue has failed to cover in 8 of the 9 losses, including each of its last 5 games as a double-digit underdog. It has scored 10 points or less in 5 of its last 7 games and has lost 5 games by 35-plus points. Michigan State has scored 32 or more points in 2 of its last 4 home games.

Over/Under

BET UNDER 48.5 (-110).

Purdue’s offense has struggled this season, scoring no points twice in its last 4 games and 10 or fewer points in 6 of the last 9 games. Michigan State has also struggled offensively, scoring 17 or fewer points in each of its last 3 weeks and in 5 of its last 6 games. Both teams struggle on defense as well, but neither will be able to produce enough offense for the Over to hit.

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