What will the Detroit Lions look like when they host the San Francisco 49ers in Week 1 of the 2021 NFL season? Now that the 53-man roster is established, we have a pretty good idea of who will take to Ford Field when the Dan Campbell era begins for real on Sunday, Sept. 12th.
There are a couple more moves the team could make, and lingering injuries with a couple of projected starters also leaves some room for a practice squad call-up. But overall, this is the projected depth chart for the Lions for Week 1.
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