Philadelphia Eagles at Dallas Cowboys odds, picks and prediction

Previewing the Philadelphia Eagles at Dallas Cowboys Week 16 betting odds and lines, with NFL betting picks, tips and predictions.

The Philadelphia Eagles (4-9-1) visit the Dallas Cowboys (5-9) Sunday for a 4:25 p.m. ET kickoff at AT&T Stadium. Below, we preview the Eagles-Cowboys betting odds and lines and make our NFL picks and predictions.

Eagles at Cowboys: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 2:52 p.m. ET.

  • Money line: Eagles -160 (bet $160 to win $100) | Cowboys +135 (bet $100 to win $135)
  • Against the spread/ATS: Eagles -3 (-115) | Cowboys +3 (-105)
  • Over/Under: 49.5 (O: -110 | U: -110)

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Eagles at Cowboys: Game notes

  • Eagles QB Jalen Hurts will make his third straight start in place of the underperforming QB Carson Wentz. Hurts is 1-1 in his two starts with the offense averaging 25.0 PPG. That’s nearly a field goal better than the team’s overall offensive production of 21.6 PPG, which is 25th in the NFL.
  • The Cowboys have looked like an NFL caliber offense in recent weeks. QB Andy Dalton is back under center after a bout with a concussion and COVID-19. He has led the team to its first consecutive wins this season, something QB Dak Prescott was unable to do. The Cowboys have posted 71 total points over the past two outings.
  • Philadelphia won 23-9 against visiting Dallas in the first meeting on Sunday Night Football in Week 8, covering a 10.5-point number. That was the game QB Ben DiNucci started for the Cowboys, and the offense was a complete and utter disaster.
  • The Cowboys are 1-3 SU/0-4 ATS against the NFC East this season. The Eagles are 2-2 SU/1-3 ATS inside the division.
  • Philly is 0-5 ATS in the past five on the road, and 1-6 ATS in its past seven as a favorite. Dallas is just 2-5 ATS in the past seven at home, but 6-0 ATS in the past six as a home underdog.

Eagles at Cowboys: Key injuries

Eagles

  • DT Fletcher Cox (neck) questionable
  • LB Duke Riley (biceps) questionable
  • DE Josh Sweat (wrist) out
  • CB Kevon Seymour (knee) out

Cowboys

  • RB Ezekiel Elliott (calf) questionable
  • CB Rashard Robinson (knee) out
  • LB Leighton Vander Esch (ankle) out
  • S Xavier Woods (ribs) out

Eagles at Cowboys: Odds, betting lines, predictions and picks

Prediction

Eagles 27, Cowboys 20

Money line (?)

The EAGLES (-160) are an OK play on the road. They have really looked a lot better with Hurts under center. The offensive line has struggled and been injury plagued, but the mobility of Hurts has helped to mask that a little bit.

Against the spread (?)

The EAGLES -3 (-115) are a good play as the favorite has cashed in eight of the past 10 meetings in this series. More important than trends, however, as neither of these quarterbacks have started a game in any of those 10 outings, is the injury report. The Cowboys have several key defenders banged up and in danger of sitting, and Zeke might be out again this week as well.

Over/Under (?)

UNDER 49.5 (-110) is worth a look even though the Cowboys defense has been a sieve lately. The Under has cashed in each of the past four for Philly as a favorite, and the Under is 4-0 in its past four against teams with a losing record. The Over is 7-2 in the past nine for Dallas at home, but the Under is 2-1 in its past three divisional games.

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