Philadelphia 76ers at Los Angeles Lakers odds, picks and predictions

Analyzing Friday’s Philadelphia 76ers at Los Angeles Lakers odds and lines, with NBA expert picks, predictions and best bets.

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The Philadelphia 76ers (38-31) and Los Angeles Lakers (37-32) meet Friday. Tip-off from Crypto.com Arena is set for 10:30 p.m. ET (NBA TV). Let’s analyze BetMGM Sportsbook’s lines around the 76ers vs. Lakers odds and make our expert NBA picks and predictions.

Season series: 76ers lead 1-0

The 76ers opened a 4-game Western Conference road trip with a 115-102 loss to the Phoenix Suns Wednesday. F Tobias Harris (ankle) missed a 3rd straight game for the 76ers, who have lost 6 of 9 after failing to cover as 9.5-point underdogs.

The Lakers snapped a 2-game skid with a cover as 9-point home favorites in a 136-105 win over the Atlanta Hawks Monday. They are currently in 9th place in the West, meaning they would have to win 2 play-in games to make the playoffs. They trail the Dallas Mavericks by 3½ games for the No. 6 seed.

In their 1st meeting (Nov. 27), the 76ers covered as 5.5-point favorites in a 138-94 victory with the Over (230.5) cashing in Philadelphia. The 44-point loss remains the worst defeat of F LeBron James‘ career.

76ers at Lakers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:15 p.m. ET.

  • Moneyline (ML): 76ers +240 (bet $100 to win $240) | Lakers -300 (bet $300 to win $100)
  • Against the spread (ATS): 76ers +7.5 (-115) | Lakers -7.5 (-105)
  • Over/Under (O/U): 224.5 (O: -110 | U: -110)

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76ers at Lakers key injuries

76ers

  • Joel Embiid (knee) out
  • Tobias Harris (ankle) questionable
  • De’Anthony Melton (back) out

Lakers

  • C Anthony Davis (Achilles) probable
  • LeBron James (ankle) questionable

For most recent updates: Official NBA injury report.

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76ers at Lakers picks and predictions

Prediction

Lakers 123, 76ers 114

Moneyline

The 76ers are 17-16 on the road this season and have lost 4 of their last 5 away games.

The Lakers (-300) are 24-12 at home this season and have won 3 of their last 4 games at Crypto.com Arena.

With no Embiid or Melton, and perhaps no Harris, it’s too much to expect the outright Philly win, and betting the Lakers at -300 just isn’t a good single bet. Include a Lakers win in a parlay bet, but don’t make that bet alone.

PASS.

Against the spread

The 76ers have not covered the spread in a loss since Jan. 27. They are 8-9 ATS as road dogs.

The Lakers have covered the spread in 4 straight wins and in 15 of their last 18 victories.

BET LAKERS -7.5 (-105).

Over/Under

The Nov. 27 meeting had 232 total points.

The Sixers’ last 9 games have not reached 225 points, but the Lakers’ last 6, and 14 of their last 16, have had 225 or more total points.

The Lakers have scored 120 or more in 5 of their last 6 games.

BET OVER 224.5 (-110).

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