Philadelphia 76ers at Cleveland Cavaliers odds, picks and predictions

Analyzing Friday’s Philadelphia 76ers at Cleveland Cavaliers odds and lines, with NBA expert picks, predictions and best bets.

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The Cleveland Cavaliers (44-29) welcome the Philadelphia 76ers (39-34) to Rocket Mortgage FieldHouse Friday. Tip is set for 7:30 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the 76ers vs. Cavaliers odds and make our expert NBA picks and predictions.

Season series: 76ers lead 2-1; Philadelphia beat Cleveland twice in February and is 2-1 against the spread (ATS) in the 3 games

The 76ers are coming off a 108-107 home loss to the LA Clippers Wednesday, covering as a 6.5-point underdog. They have lost 4 of their last 5 games yet are 5-2 ATS over their last 7. Philadelphia is 39-33-1 ATS on the season. The 76ers, with C Joel Embiid still sidelined with a knee injury, are led by G Tyrese Maxey, who is averaging 25.8 points per game (PPG).

The Cavaliers lost to the Charlotte Hornets 118-111 on the road Wednesday, failing to cover as a 9.5-point favorite. They have lost 4 of their last 5 games and are 1-4 ATS in that span. Cleveland is 35-38 ATS on the season, and is 3-2 ATS in its last 5 home games. It is led by G Donovan Mitchell, who is averaging 27.4 PPG.

76ers at Cavaliers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:51 a.m. ET.

  • Moneyline (ML): 76ers +265 (bet $100 to win $265) | Cavaliers -330 (bet $330 to win $100)
  • Against the spread (ATS): 76ers +8 (-110) | Cavaliers -8 (-110)
  • Over/Under (O/U): 212.5 (O: -108 | U: -112)

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76ers at Cavaliers key injuries

76ers

  • F Robert Covington (knee) out
  • C Joel Embiid (knee) out

Cavaliers

  • G Darius Garland (ankle) probable
  • G Donovan Mitchell (nasal) questionable

For most recent updates: Official NBA injury report.

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76ers at Cavaliers picks and predictions

Prediction

Cavaliers 107, 76ers 103

Moneyline

PASS.

The Cavaliers are 1-4 in their last 5, so while they may be the better and deeper side and Philly is without its top player, it isn’t worth a moneyline play at an expensive -330.

Against the spread

BET 76ERS +8 (-110).

The 76ers haven’t consistently won without Embiid on the court, but they have covered at a high rate as of late. They have been an underdog in 5 straight games and are 3-2 ATS in those. Philly is 5-2 ATS in its last 7 as well.

The Cavaliers are the opposite. They are 2-5 straight up and ATS in their last 7 games, failing to cover in every loss. The Cavs have lost 3 of their last 4 games at home.

Considering those trends, back 76ERS +8 (-110) to keep things at close.

Over/Under

LEAN UNDER 212.5 (-112).

Neither offense has been consistent over the last few weeks, and that’s why the Under is the better option. The Cavaliers have scored 105 or fewer in 4 of their last 7, and they have scored 91 or fewer in 2 of their last 3.

Cleveland’s top option, Mitchell, is also questionable, although the spread indicates he’s likely to take the court. The 76ers have gone Under 105 in 4 of their last 6 and Under 100 in 2 of their last 3. Philadelphia is 2-5 O/U in its last 7 games.

Take UNDER 212.5 (-112).

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