Penn State vs. Ohio: Prediction, point spread, odds, best bet

The odds for Penn Stae’s home opener against Ohio are out from Tipico, and the Nittany Lions are a solid home favorite.

After an exciting start to the 2022 college football season, Penn State prepares for its home opener in Beaver Stadium in Week 2. This week the Nittany Lions will host the Ohio Bobcats out of the MAC as Ohio is also coming off a thrilling start to their season. Ohio held on to a lead in their 2022 debut in Week 1 against FAU for a 41-38 victory in which quarterback Kurtis Rourke passed for 345 yards and four touchdowns.

Penn State’s secondary will have to be up to the task as Ohio comes in ready to throw the football all around the field. Penn State is also hoping to clean up a few areas of concern after its season opener at Purdue, including the stability of the offensive line and the effectiveness of the running game.

Perhaps not too surprisingly, Penn State will play its home opener as a big favorite against the Bobcats. The opening line from Tipico Sportsbook places plenty of confidence in Penn State in its home opener this Saturday.

Here is a full rundown of the odds for this week’s game.