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The Ole Miss Rebels (4-1, 0-1 SEC) meet the South Carolina Gamecocks (3-1, 1-1) in Columbia Saturday. Kickoff at Williams-Brice Stadium is set for 3:30 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s college football odds around Ole Miss vs. South Carolina odds, and make our expert college football picks and predictions.
Ole Miss dropped from No. 5 to No. 11 in the US LBM Coaches Poll following a 20-17 home loss as a 15.5-point favorite to unranked Kentucky Sept. 28. The loss was only Mississippi’s 2nd defeat since Sept. 30, 2023. The Rebels were undone by the Wildcats controlling the football for 39 minutes and 43 seconds, while Ole Miss’ time of possession was 20 minutes and 17 seconds.
South Carolina heads into this contest off a bye week. The Gamecocks likely needed it as they’re set to open a tough stretch of their schedule with consecutive games against Ole Miss, No. 2 Alabama, No. 17 Oklahoma and No. 21 Texas A&M. The Gamecocks defeated Akron 50-7 as 24.5-point home favorites in their last outing (Sept. 21).
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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Ole Miss at South Carolina odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 6:20 a.m. ET.
- Moneyline: Ole Miss -350 (bet $350 to win $100) | South Carolina +260 (bet $100 to win $260)
- Against the spread (ATS): Ole Miss -9.5 (-110) | South Carolina +9.5 (-110)
- Over/Under (O/U): 53.5 (O: -110 | U: -110)
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Ole Miss at South Carolina picks and predictions
Prediction
Ole Miss 27, South Carolina 19
Moneyline
No interest. PASS.
Against the spread
USC is 3-1 ATS across its last 4 games as a home underdog.
Ole Miss lost to Kentucky which USC downed 31-6 back on Sept. 7. Look for the Gamecocks to come up with enough havoc plays on defense and explosive plays on offense to keep this one interesting.
FanDuel Sportsbook offers a play with better value on the home side: Consider a partial-unit play on SOUTH CAROLINA +9.5 (-108).
The last 2 meetings in this series produced 2 Overs and a combined 193 points. But look for the Under to have the better leverage in Saturday’s game.
Ole Miss has run a ton of plays through 5 games. Look for South Carolina, which runs a high rate of rushing plays, to want to slow things down.
Both sides have been excellent in preventing 6-pointers in the red zone.
BACK THE UNDER 53.5 (-110).
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