The Ohio State Buckeyes (5-0, 2-0 Big Ten) and the Michigan State Spartans (2-3, 0-2) meet in a conference game Saturday at Spartan Stadium in East Lansing. Kickoff is scheduled for 4 p.m. ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Ohio State vs. Michigan State odds, and make our expert college football picks and predictions.
Ohio State thumped Rutgers 49-10 last week in The ‘Shoe and has outscored 2 conference opponents 101-31 over the past 2 games. The Over has cashed in 3 consecutive games for the Buckeyes, who lead the nation with 48.8 PPG.
Michigan State started out this season with a high ranking, but it has dropped 3 games in a row to Washington, Minnesota and Maryland. The Spartans are also 0-3 ATS in the past 3 outings, while the Under has cashed at a 4-1 clip through 5 contests.
Ohio State is No. 3 in the AFCA Coaches Poll powered by USA TODAY Sports.
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Ohio State at Michigan State odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7 a.m. ET.
- Moneyline (ML): Ohio State -5000 (bet $5,000 to win $100) | Michigan State +1500 (bet $100 to win $1,500)
- Against the spread (ATS): Ohio State -27.5 (-107) | Michigan State +27.5 (-115)
- Over/Under (O/U): 64.5 (O: -120 | U: -105)
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Ohio State at Michigan State picks and predictions
Prediction
Ohio State 48, Michigan State 17
Moneyline
Betting Ohio State (-5000) would net you a $2 profit for every $100 bet. No one needs 2 dollars that badly.
PASS.
Against the spread
OHIO STATE -27.5 (-107) is a slightly risky play laying just short of 4 TDs on the road, but it is worth it.
The Buckeyes have a high-octane offense capable of scoring on any play. Lately, the Spartans have had a struggling defense capable of allowing a score on any play.
Ohio State is 2-0-1 ATS across the past 3 outings and will start fast and finish faster, adding to the woes of Michigan State, a team on an 0-3 SU/ATS skid.
Over/Under
OVER 64.5 (-120) is worth playing, but there is some risk. We have the No. 1 scoring team in the nation on one side, but we also have a struggling Michigan State team which will likely need to score at least 2 TDs to help this one get across the finish line. Sparty has 20 total points and 3 TDs in the past 2 games. Be careful, and play this one lightly.
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