The Notre Dame Fighting Irish and Florida State Seminoles meet Sunday at Doak Campbell Stadium in Tallahassee, Fla. Kickoff is scheduled for 7:30 p.m. ET. Below, we look at the Notre Dame vs. Florida State odds and lines, and make our expert college football picks, predictions and bets.
Notre Dame heads into the season at No. 7 in the AFCA Coaches Poll powered by USA TODAY Sports. The Irish faced the Seminoles in October 2020, and Notre Dame came away with a 42-26 victory but failed to cover a 21-point spread.
The Irish will have a much different look, however, as QB Ian Book has graduated. Wisconsin transfer QB Jack Coan takes the reins of the offense, and he is more of a short-to-intermediate route thrower, rather than a big downfield threat.
Look for Notre Dame to run the ball with its tremendous one-two backfield punch, of RBs Chris Tyree and Kyren Williams. When they’re in the red zone, look for TE Michael Mayer to be targeted frequently.
Florida State also has a new signal-caller. Or does it? Head coach Mike Norvell isn’t expected to name a starter until game time, either redshirt sophomore Jordan Travis, or incoming transfer QB McKenzie Milton, formerly of UCF.
Notre Dame at Florida State odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 8:45 a.m. ET.
- Money line: Notre Dame -280 (bet $280 to win $100) | Florida State +220 (bet $100 to win $220)
- Against the spread (ATS): Notre Dame -7.5 (-102) | Florida State +7.5 (-122)
- Over/Under (O/U): 55.5 (O: -108 | U: -112)
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Notre Dame at Florida State odds, lines, picks and predictions
Prediction
Notre Dame 30, Florida State 19
Money line
Notre Dame (-280) will cost you more than two and a half times your potential return, and that’s just too risky with a new quarterback in a road opener.
AVOID.
Against the spread
NOTRE DAME -7.5 (-102) is a slam-dunk play.
Notre Dame is the ranked and better team. Florida State has some nice pieces coming over through the transfer portal, but it’s going to take time for this team to jell.
Over/Under
UNDER 55.5 (-112) is a great play as well and I love a Notre Dame/Under parlay. We will see a transfer quarterback for the Irish, and we’re expecting to see a transfer quarterback see meaningful snaps for the home side, too. There is a lot of change going on.
In addition, Notre Dame is expected to lean heavily upon its two returning tailbacks. Running teams keep the clock running and that’s great news for Under bettors.
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