Notre Dame at Duke odds, picks and predictions

Analyzing Tuesday’s Notre Dame at Duke odds and lines, with college basketball expert picks, predictions and best bets.

The Notre Dame Fighting Irish (10-15, 2-12 ACC) and Duke Blue Devils (17-8, 8-6) meet Tuesday at Cameron Indoor Stadium in Durham, N.C. Tip-off is scheduled for 7 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Notre Dame vs. Duke game odds, and make our expert college basketball picks, predictions and bets.

Notre Dame has been in a tailspin in coach Mike Brey’s final season at the helm, although it was reported he won’t be officially retiring after his tenure with the Fighting Irish. ND has dropped 3 games in a row, and 7 of its last 8, while going just 4-14 against the spread (ATS) across the past 18 games overall.

Duke had posted 3 straight impressive wins from Jan. 28-Feb. 4, including a win in the Battle of the Blues over rival North Carolina, but it has suffered back-to-back losses on the road at Miami and Virginia. The Blue Devils are also just 3-11 ATS in the past 14 games overall, so something’s gotta give.

Check out: USA TODAY Sports Coaches Poll

Can you survive? New pro and college basketball survivor pools are here at USA TODAY Sports! Free to play; terms and conditions apply. Join now!

Notre Dame at Duke odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:43 a.m. ET.

  • Moneyline (ML): Notre Dame +500 (bet $100 to win $500) | Duke -800 (bet $800 to win $100)
  • Against the spread (ATS): Notre Dame +11.5 (-105) | Duke -11.5 (-115)
  • Over/Under (O/U): 140.5 (O: -110 | U: -110)

Catch the excitement and bet with Tipico

Double Down, Ohio! Deposit $200, Get $250. Bet now!

In Colorado and New Jersey, claim your 100% Deposit Match up to $250 now. Bet now! 21+, see Tipico.com for Terms and Conditions.

Notre Dame at Duke picks and predictions

Prediction

Duke 75, Notre Dame 67

Moneyline

PASS.

Duke (-800) is way too expensive, even to include in a parlay. Focus on the spread or total in this game instead.

Stream select live college basketball games and full replays: Get ESPN+

Against the spread

NOTRE DAME +11.5 (-105) is worth the play, as the 2023 version of Duke has been mediocre at best and has no business laying double digits against anyone right now.

The last time Duke laid double digits was New Year’s Eve against Florida State, covering in a win. However, it is just 1-4 ATS in the past 5 games overall when laying 10 or more points.

Over/Under

OVER 140.5 (-115) is the lean, but play it lightly.

The Over has been the dominant side for the Fighting Irish of late, going 8-1-2 in the past 11 games overall and cashing at an 18-7-1 clip in the past 26 games on the road.

The Over is also 20-7-2 in the past 29 home games for Duke when facing a team with a losing road record.

Play our free daily Pick’em Challenge and win! Play now!

Want action on this basketball game or any other sports contest? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Kevin J. Erickson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1667]