North Carolina at Duke odds, picks and predictions

Analyzing Saturday’s North Carolina Tarheels at Duke Blue Devils odds and lines, with college football expert picks, predictions and best bets.

The No. 25 North Carolina Tar Heels (5-1, 2-0 ACC) and the Duke Blue Devils (4-2, 1-1) meet at Wallace Wade Stadium in Durham, N.C. Kickoff is scheduled for 8 p.m. ET (ACC Network). Below, we analyze Tipico Sportsbook‘s lines around the North Carolina vs. Duke odds, and make our expert college football picks and predictions.

The Tar Heels eased by Miami on the road, winning 27-24 as a 4-point underdog. It was the second straight win since a 45-32 loss at home to Notre Dame back on Sept. 24. UNC has covered 4 of its past 5 games overall.

The Blue Devils opened the season 3-0 SU/2-1 ATS, but they have dropped 2 in a row. At home, however, Duke is 3-0 SU/2-1 ATS, and unbeaten in both games against FBS opponents. The Under is 4-1-1 in the past 6 games overall for Duke, too.

North Carolina is No. 25 in the AFCA Coaches Poll powered by USA TODAY Sports.

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North Carolina at Duke odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:45 a.m. ET.

  • Moneyline (ML): North Carolina -270 (bet $270 to win $100) | Duke +220 (bet $100 to win $220)
  • Against the spread (ATS): North Carolina -7.5 (-105) | Duke +7.5 (-120)
  • Over/Under (O/U): 68.5 (O: -107 | U: -115)

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North Carolina at Duke picks and predictions

Prediction

North Carolina 43, Duke 32

Moneyline

North Carolina (-270) will cost you over 2 1/2 times your potential return, and that’s a big risk, especially in a rivalry game in their place. Duke (+220) has at least been respectable this season, and certainly no pushover.

PASS.

Against the spread

NORTH CAROLINA -7.5 (-105) is worth playing, even though 7-and-a-hook isn’t the most attractive number.

UNC has won the past 2 meetings by 31 or more points. While Duke +7.5 (-120) is a much better team this season, and this will be a much tougher test for Carolina, roll with the Heels laying the points.

Over/Under

OVER 68.5 (-107) is the lean here. The last time these teams met in Durham, we had a total of 80 points on the scoreboard. Before that, in 2018, the teams posted 77 total points at Wallace Wade Stadium. In fact, in 4 of the past 5 meetings in Durham, we have had at least 65 total points on the board. When UNC heads up US 15-501 to Durham, plenty of offense occurs.

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