NFL picks against the spread for Week 4 late afternoon games

These are Jess Root’s betting game picks for the four late afternoon games in Week 4.

In Week 4, there are eight early games on Sunday kicking off at 1 p.m. ET. Another four start at 4:05 p.m. ET (games on FOX) or 4:25 p.m. ET (games on CBS).  If you are one to place a wager or two on NFL games, this info is for you.

Below are my NFL picks against the spread for all those late afternoon games. I have selections for the winners on the moneyline, the spread and the total.

Odds come from BetMGM Sportsbook.

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NFL picks against the spread Week 4 early games

Commanders at Cardinals

  • Moneyline: Cardinals -175
  • Spread: Cardinals -3.5 (+100)
  • Total: Over 50.5 (-110)

Patriots at 49ers

  • Moneyline: 49ers -650
  • Spread: 49ers -10.5 (-105)
  • Total: Under 40.5 (-110)

Browns at Raiders

  • Moneyline: Browns +110
  • Spread: Browns +2 (-110)
  • Total: Over 37 (-110)

Chiefs at Chargers

  • Moneyline: Chiefs -400
  • Spread: Chargers +7.5 (-110)
  • Total: Over 39.5 (-110)

Get more Cardinals and NFL coverage from Cards Wire’s Jess Root and others by listening to the latest on the Rise Up, See Red podcast. Subscribe on SpotifyYouTube or Apple podcasts.

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