New York Yankees at San Francisco Giants odds, picks and predictions

Analyzing Saturday’s New York Yankees at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (29-29) welcome the New York Yankees (40-19) to Oracle Park Saturday for the 2nd of their 3-game series. First pitch is set for 10:05 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Yankees vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Yankees lead 1-0

The Yankees opened up the lone regular season series between these 2 teams with a 6-2 win Friday. They jumped out to a 3-1 lead after the 3rd and never looked back.

The Yankees continued their win streak, having now claimed victory in 3 straight and covering in 2 of those. They are 7-2 over their last 9 games. New York sits atop the AL East and is 33-25-1 against the spread (ATS) on the season.

The Giants, who sit 3rd in the NL West, have won 6 of their last 9 games and are 28-30 ATS on the season. San Francisco has won 6 of its last 8 home games and is coming off a series in which it won 2 of 3 against the NL East-leading Philadelphia Phillies.

Yankees at Giants projected starters

RHP Cody Poteet vs. RHP Logan Webb

Poteet (1-0, 1.50 ERA) makes his 2nd start. He has a 1.00 WHIP, 0.0 BB/9 and 6.0 K/9 through 6 IP.

  • Last start: Win, 6 IP, 1 ER, 6 H, 0 BB, 4 K in an 8-2 road win over the Cleveland Guardians April 13
  • 2022 road splits (was out all of 2023 recovering Tommy John surgery): 0-1, 3.97 ERA (11 1/3 IP, 5 ER), 6 H, 1 HR, 9 BB, 6 K in 1 start and 5 relief appearances with the Miami Marlins
  • Has yet to face the Giants

Webb (4-4, 2.74 ERA) makes his 13th start. He has a 1.26 WHIP, 2.4 BB/9 and 7.6 K/9 through 72 1/3 IP.

  • Last start: No-decision, 7 IP, 0 ER, 3 H, 1 BB, 8 K in a 4-3 road loss to the New York Mets Sunday
  • 2024 home splits: 3-1, 1.03 ERA (35 IP, 4 ER), 29 H, 0 HR, 7 BB, 23 K in 5 starts
  • Career vs. Yankees: 0-1, 6.00 ERA (6 IP, 4 ER), 1.00 WHIP, 18.0 K/9 in 1 start

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Yankees at Giants odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:40 a.m. ET.

  • Moneyline (ML): Yankees +100 (bet $100 to win $100) | Giants -118 (bet $118 to win $100)
  • Run line (RL)/Against the spread (ATS): Yankees -1.5 (+172) | Giants +1.5 (-210)
  • Over/Under (O/U): 7.5 (O: -112 | U: -108)

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Yankees at Giants picks and predictions

Prediction

Giants 5, Yankees 3

Moneyline

BET GIANTS (-118).

Throughout his career, Poteet is 7-13 when making an appearance, and in his 2nd start of the season against a solid Giants offense that sits 10th in batting average. He’ll have a tough task. They have scored at least 6 runs in 6 of their last 10 games.

While the Yankees have won consistently as of late, they have scored 3 or fewer in 3 of their last 5 and will have a significant pitching disadvantage with Webb having started the season strong.

Expect San Fran to use that advantage to come out on top and back GIANTS (-118).

Run line/Against the spread

PASS.

The Giants are far too expensive as a run-line underdog here and aren’t worth any play at -210. Similarly, the Yankees, with an inexperienced and potentially risky Poteet, aren’t worth a play as a run-line favorite.

Over/Under

BET OVER 7.5 (-112).

The Yankees offense is starting to click, having scored at least 6 runs in 2 of their last 3 games. They have gone Over in 7 of their last 12 as well.

The Giants, who are 30-26-2 O/U on the season, have topped the total in 7 of their last 10 games and have allowed at least 5 runs in 6 of those while scoring at least 6 runs in 6 of them.

Considering those trends from both sides, back OVER 7.5 (-112).

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