New York Jets at Carolina Panthers odds, picks and prediction

Analyzing the New York Jets at Carolina Panthers Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The New York Jets and Carolina Panthers meet Sunday at Bank of America Stadium in Charlotte. Kickoff is scheduled for 1 p.m. ET and the game is televised on CBS. Below, we look at the Jets vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

The Jets traded QB Sam Darnold to the Panthers and then selected QB Zach Wilson out of BYU with the No. 2 overall pick in the 2021 NFL Draft. As luck has it, these two players and teams face each other in Week 1.

Wilson looked very good in the preseason, but he’ll be without one of his top receivers with WR Jamison Crowder on the COVID-19 list and ruled out by head coach Robert Saleh.

Darnold looks to exact a little revenge on the team which gave up on him, and show the Jets what they could’ve been if they had NFL-caliber receivers and a top-notch running back. That’s what he has in Charlotte with the Panthers.

Also see: NFL team win totals

Jets at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 12:30 p.m. ET.

  • Money line: Jets +170 (bet $100 to win $170) | Panthers -210 (bet $210 to win $100)
  • Against the spread (ATS): Jets +4.5 (-115) | Panthers -4.5 (-107)
  • Over/Under (O/U): 45.5 (O: -105 | U: -115)

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Jets at Panthers key injuries

Jets

  • WR Keelan Cole (knee) questionable
  • WR Jamison Crowder (COVID-19) out
  • RB La’Mical Perine (foot) questionable
  • Sharrod Neasman (hamstring) out

Panthers

  • No notable injuries

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Jets at Panthers odds, lines, predictions and picks

Prediction

Panthers 27, Jets 20

Money line

The new-look Panthers (-210) will cost you more than two times your potential return against the Jets. Carolina enters the game healthier than its counterparts, but it’s still a risky play at this price.

The Panthers lost their last two regular-season openers, both at home, and they failed to cover in each while the Over connected.

AVOID and look to the spread.

Also see: Week 1 staff picks

Against the spread

While the Jets might have a lot of the focus on them in this matchup because of their shiny new quarterback, this is a redemption story and the PANTHERS -4.5 (-107) are beginning a new era.

Darnold looks to keep his old organization down, and he’ll do just that with former Jets WR Robby Anderson, WR DJ Moore and RB Christian McCaffrey helping him out.

The Jets went 1-4 ATS in their last five regular-season openers, and they’re 1-8 ATS in their last nine September games.

Over/Under

The OVER 45.5 (-105) is worth a small-unit play. Darnold and Wilson will be locked in a battle here, and it has the chance to be a very exciting game.

The Over cashed in each of the last two regular-season openers for the Panthers, and we should see a third straight with a game in the upper 40s. Be patient, though, as things could get off to a slow start before the quarterbacks get their sea legs.

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