The New Orleans Saints (11-4) and Carolina Panthers (5-10) wrap up the regular season Sunday with a 4:25 p.m. ET kickoff at Bank of America Stadium. Below, we preview the Saints-Panthers betting odds and lines and make our NFL picks and predictions.
Saints at Panthers: Betting odds, spread and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 10 a.m. ET.
- Money line: Saints -275 (bet $275 to win $100) | Panthers +225 (bet $100 to win $225)
- Against the spread/ATS: Saints -6 (-110) | Panthers +6 (-110)
- Over/Under: 46.5 (O: -110 | U: -110)
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Saints at Panthers: Game notes
- The Saints have wrapped up the NFC South Division title, but they have their eyes on a larger prize. With a little help, they could still end up with the No. 1 seed in the NFC and home-field advantage throughout the playoffs.
- The Panthers won the Ron Rivera Bowl last week, topping the Washington Football Team by a 20-13 count on the road. The Panthers are 2-3 straight up and 4-1 ATS across their past five games.
- The last time these teams met in New Orleans in Week 7, the Saints edged the Panthers 27-24 with Carolina covering a plus-7 number with the Over (49.5) connecting. The Saints are just 1-5 ATS in their past six games against the Panthers, with the underdog going 11-2 ATS across the past 13 meetings.
- New Orleans has cashed in six of its past seven games against NFC South opponents, and it is 5-1 ATS in its previous six as a favorite. The Saints are also an impressive 15-6 ATS across their past 21 as a road favorite.
- Carolina has covered in just two of its past seven inside the division, and it’s 2-8-1 ATS in its past 11 games at BoA. The Panthers are a solid 8-1 ATS in their past nine games as underdogs, although they’re just 2-5 ATS in their past seven as home dogs.
Saints at Panthers: Key injuries
Saints
- TE Josh Hill (hand) out
- RB Alvin Kamara (Reserve/COVID-19) out
- RB Latavius Murray (Reserve/COVID-19) out
- S Marcus Williams (ankle) out
Panthers
- DE Brian Burns (shoulder) doubtful
- RB Mike Davis (ankle) doubtful
- DE Yetur Gross-Matos (shoulder) questionable
- DE Austin Larkin (shoulder) questionable
- RB Christian McCaffrey (thigh) doubtful
- DE Efe Obada (shoulder, toe) questionable
- OT Russell Okung (calf) doubtful
- CB Tony Pride Jr. (hip) doubtful
Saints at Panthers: Odds, betting lines, predictions and picks
Prediction
Saints 31, Panthers 20
Money line (?)
The Saints (-275) have plenty to play for, but they’re still a risky play on the road laying nearly three times your potential return. Instead, look to the spread.
AVOID.
Against the spread (?)
The SAINTS -6 (-110) are an attractive play on the road laying less than a touchdown but know Joey Public will also be going with you at nearly a 2-to-1 clip.
Not many are giving the Panthers a chance to finish on a high note, and with so much on the line for New Orleans, I’m not giving them much of a chance, either. It is a little disconcerting that RB Alvin Kamara will be missing in action due to COVID-19, so maybe go just a little lighter than normal.
Over/Under (?)
OVER 46.5 (-110) is the play, cashing in nine of the last 13 games for NOLA as a favorite while going 6-2 in its past eight as a road favorite. The Over is also 6-2 in Carolina’s past eight divisional tilts, and 18-8 in its past 26 games against winning sides.
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