New England Patriots at Arizona Cardinals odds, picks and predictions

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Two teams mired in 3-game losing streaks face off in Week 15 as the New England Patriots (3-10) visit the Arizona Cardinals (6-7). Kickoff from State Farm Stadium is at 4:25 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Patriots vs. Cardinals odds, and make our expert NFL picks and predictions.

The Pats are coming off their bye week after losing 3 straight games, the last 25-24 to the Indianapolis Colts at home in Week 13, covering the 2.5-point spread as underdogs. New England lost when Colts QB Anthony Richardson threw a 3-yard TD pass with 12 seconds left and ran a successful 2-point conversion for the win.

The Cardinals have lost 3 straight games since their bye in Week 11 and a 4-game winning streak. QB Kyler Murray was picked off twice last week in a 30-18 home loss to the Seattle Seahawks when they were 3-point favorites.

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Patriots at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 7:58 p.m. ET.

Moneyline (ML): Patriots +200 (bet $100 to win $200) | Cardinals -250 (bet $250 to win $100)
Against the spread (ATS): Patriots +6 (-110) | Cardinals -6 (-110)
Over/Under (O/U): 46 (O: -110 | U: -110)

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Patriots at Cardinals key injuries

Patriots

WR Javon Baker (concussion) out
DT Christian Barmore (not injury related-other) questionable
S Kyle Dugger (ankle) questionable
CB Christian Gonzalez (shoulder) questionable
T Vederian Lowe (shoulder) questionable
DT Jaquelin Roy (foot) injured reserve
G Cole Strange (knee) questionable
T Caedan Wallace (ankle) out

Cardinals

P Blake Gillikin (foot) out
RB Emari Demercado (back) out
CB Elijah Jones (ankle) out
DL Naquan Jones (shoulder) questionable
DL Roy Lopez (ankle) questionable

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Patriots at Cardinals picks and predictions

Prediction

Cardinals 27, Patriots 16

Moneyline

The Cardinals have faced 3 straight quality opponents in losses, teams playing great defense. The Patriots do not have a great defense. They are 21st in points allowed at 23.2 per game. They have an even worse offense, 31st in points (17 PPG) and yards. They have allowed 43 sacks and turned the ball over 9 times in their last 5 games.

Arizona’s red-zone struggles, 3-for-13 in their last 3 games, should go away and they should get the run game going, as the Pats have allowed over 100 rushing yards to an opponent in 9 of their last 11 games.

But don’t bet the Cardinals at -250 as it isn’t worth the action.

PASS.

Against the spread

The Cardinals have lost the last 2 games in which they were favored, but they have covered the spread in all 6 of their wins this season.

The Pats have lost 6 times by at least 6 points.

BET CARDINALS -6 (-110).

Over/Under

Before giving up 30 points to the Seahawks last week, the Cardinals went 3 consecutive home games without allowing a touchdown. Two of those games were against the Jets and Bears, two teams struggling like the Patriots.

BET UNDER 46 (-110).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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