Minnesota Twins at Toronto Blue Jays odds, picks and predictions

Analyzing Friday’s Minnesota Twins at Toronto Blue Jays odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (22-15) and Toronto Blue Jays (17-20) open a 3-game series Friday. First pitch from Rogers Centre is set for 7:07 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Twins vs. Blue Jays odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; split last season 3-3

Minnesota routed the Seattle Mariners 11-1 Friday while cashing as a -110 home favorite. The Twins jumped out to a 5-0 lead in the 1st inning, from there they never allowed the game to even get close. RHP Pablo Lopez picked up the win as he allowed 1 earned run on 4 hits and 1 walk with 10 K’s in 6 1/3 innings.

Toronto beat the Philadelphia Phillies 5-3 Wednesday while cashing as a +144 road underdog. RHP Chris Bassitt picked up the win, allowing 2 earned runs on 3 hits and 2 walks with 6 K’s in 6 1/3 innings. The Blue Jays had 12 hits and 14 total bases to Philly’s 7 hits and 10 total bases in the win.

Twins at Blue Jays projected starters

RHP Joe Ryan vs. LHP Yusei Kikuchi 

Ryan (1-2, 3.54 ERA) makes his 8th start. He has a 1.01 WHIP, 1.3 BB/9 and 10.2 K/9 in 40 2/3 innings.

  • Last start: Loss, 6 IP, 3 ER, 4 H, 1 BB, 5 K in 9-2 home loss vs. Boston Red Sox Sunday
  • Career vs. Toronto: 0-0, 4.50 ERA (6 IP, 3 ER), 6 H, 1 BB, 4 K in 1 start, a 9-4 road win June 10, 2023

Kikuchi (2-2, 2.72 ERA) makes his 8th start. He has a 1.16 WHIP, 2.0 BB/9 and 9.8 K/9 in 39 2/3 innings.

  • Last start: No-decision, 6 IP, 1 ER, 6 H, 1 BB, 7 K in 9-3 loss at Washington Nationals Friday
  • Career vs. Minnesota: 1-1, 3.38 ERA (26 2/3 IP, 10 ER), 27 H, 7 BB, 26 K across 5 starts — no-decision in 1 start vs. Twins in 2023 (5 IP, 2 ER)

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Twins at Blue Jays odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:25 a.m. ET.

  • Moneyline (ML): Twins -104 (bet $104 to win $100) | Blue Jays -112 (bet $112 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+152) | Blue Jays +1.5 (-184)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

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Twins at Blue Jays picks and predictions

Prediction

Twins 5, Blue Jays 4

Moneyline

BET TWINS (-104).

Minnesota has won back-to-back games and is 3-1 in its last 4 and 8-2 in its last 10 outings. The Twins have also won back-to-back games vs. Toronto and are 4-1 in the last 5 matchups. Minnesota is 2-1 in its last 3 matchups vs. the Blue Jays in Toronto.

Run line/Against the spread

PASS.

I fully expect the Blue Jays to cover here as +1.5 (-184) underdogs, especially given that recent matchups between these squads have been very competitive with the Twins only leading 6-4 in the last 10. However, the line is far too risky to bet on, so bet on the moneyline and/or total instead.

Over/Under

LEAN OVER 7.5 (-115).

The Over has hit in 3 consecutive games for Minnesota and is 4-1 in its last 5. For Toronto, the Over is 4-1 in its last 5 games. The Over has also been slightly safer for the Twins this season at 19-17-1 on the year.

This is only a lean because the Under has hit in back-to-back Minnesota-Toronto matchups and is 4-2 in the last 6.

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