Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (80-71) and Cleveland Guardians (87-65) meet for the 3rd game of a 4-game series Wednesday. First pitch from Progressive Field is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Cleveland leads 8-3

Minnesota beat Cleveland 4-1 Tuesday as a +121 road underdog. The Twins scored 3 unanswered runs after the 5th inning to break the 1-1 tie.

Guardians SP Gavin Williams allowed 2 earned runs on 5 hits and 2 walks with 7 K’s in 5 innings and recorded the loss. The setback ended a 3-game win streak for the Guardians, who are battling for the division title with Minnesota and the Kansas City Royals.

Twins at Guardians projected starters

RHP Bailey Ober vs. RHP Tanner Bibee

Ober (12-7, 3.90 ERA) makes his 29th start. He has a 0.99 WHIP, 2.3 BB/9 and 9.4 K/9 through 161 2/3 innings.

  • Last start: Loss, 6 2/3 IP, 5 ER, 6 H, 2 BB, 6 K in 8-4 home defeat vs. Cincinnati Reds Friday
  • Career vs. Cleveland: 2-2, 2.13 ERA (38 IP, 9 ER), 0.90 WHIP, 8.1 K/9 in 7 starts

Bibee (11-8, 3.60 ERA) makes his 30th start. He has a 1.14 WHIP, 2.3 BB/9 and 9.8 K/9 through 160 innings.

  • Last start: Loss, 6 IP, 3 ER, 8 H, 0 BB, 9 K in 3-1 home setback vs. Tampa Bay Rays Friday
  • Career vs. Minnesota: 2-0, 2.73 ERA (33 IP, 10 ER), 1.18 WHIP, 10.9 K/9 in 6 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated Tuesday at 12:05 a.m. ET.

  • Moneyline (ML): Twins +100 (bet $100 to win $100) | Guardians -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+170) | Guardians +1.5 (-210)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

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Twins at Guardians picks and predictions

Prediction

Guardians 4, Twins 2

Moneyline

BET GUARDIANS (-120).

Cleveland is 3-1 in its last 4 home games and 6-3 in its last 9 overall, while the Twins are 1-3 in their last 4 on the road and 4-6 in their last 10 overall.

The Guardians are also 4-1 in the last 5 meetings between these teams in Cleveland and 7-3 in the last 10 overall.

Run line/Against the spread

PASS.

I expect the Guardians to cover here as +1.5 (-210) underdogs, but their odds are better on the ML and this line is not worth the risk. Bet the ML and/or total instead.

Over/Under

BET UNDER 7.5 (-115).

The Under has hit in 5 of Cleveland’s last 6 home games and is 8-1-1 in its last 10 overall. For Minnesota, the Under is 3-0-1 in its last 4 road games. The Under is also 3-1-1 in the last 5 meetings in Cleveland and 6-2-2 in the last 10 overall.

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