Manchester City vs. Southampton odds, picks and prediction

Below, we preview the Manchester City vs. Southampton odds and lines, and make our best EPL bets, picks and predictions.

In an action-packed EPL Saturday, Southampton (0 wins, 1 loss, 3 draws) visits Manchester City (3-1-0). The match is set to kick off at 10 a.m. ET and will be held at Etihad Stadium. Below, we preview the Manchester City vs. Southampton odds and lines, and make our best EPL bets, picks and predictions.

Since losing a 1-0 match against Tottenham to open the season (a match Man City looked dominant in), Man City has rattled off three straight wins, while defeating opponents by a combined 11-0.

It also dropped 6 goals on RB Leipzig in the opening group stage match of the Champions League. Man City will be without D Benjamin Mendy and D John Stones though, so its defense may struggle; however, City should be fine against Southampton.

Only M Stuart Armstrong has been ruled out for Southampton. It has a draw with Manchester United, while also having tied West Ham and Newcastle but losing 3-1 to Everton.

Manchester City vs. Southampton: Odds, picks and predictions

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 1 p.m. ET.

  • Money line: Manchester City -650 (bet $650 to win $100) | Southampton +1500 (bet $100 to win $1,500) | Draw +700
  • Over/Under: 3.5 (O: -102 | U: -122)

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Prediction

Manchester City 3, Southampton 1

Money line (ML)

PASS on the money line. In soccer, draws happen and just look at what Southampton was able to do to Manchester United. While I’m confident Manchester City will come out on top, the -650 price is too chalky.

While Manchester City has had three straight clean sheets, not having Stones or Mendy could start to wear down the backline. Southampton put one on Man U and two on Newcastle.

Obviously, Southampton isn’t at the same level as Man City, especially in the midfield; however, Southampton has had at least 3 shots on target in all four of its EPL matches.

I’d put half a unit on BOTH TEAMS TO SCORE (+110).

Over/Under (O/U)

BET on the OVER 3.5 (-102) as Manchester City is cooking right now and easily has the most dominant midfield in the EPL.

The combination of M Jack Grealish and M Kevin de Bruyne has been just phenomenal to watch. Add in F Raheem Sterling, and it’s an unfair collection of talent. M İlkay Gündoğan is also coming off his best professional season.

Having averaged just under 4 goals per game and taking on a weaker side in Southampton, expect Man City to get what it wants and come out on top with relative ease in this one.

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