LSU and South Carolina met for the 21st time in program history in 2015.
The Tigers were No. 7 in the country with a 4-0 record entering the game. The Gamecocks entered with a 2-3 record, and an 0-3 record in the SEC.
Tigers quarterback Brandon Harris played a stellar game under center, going 18-of-28 for 228 yards and two touchdowns.
Derrius Guice carried the ball 16 times for 161 yards and a touchdown. Travin Dural led the Tigers in receptions with four catches for 109 yards and one touchdown.
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For South Carolina, Perry Orth went 14-of-28 for 200 passing yards with two touchdowns and one interception. The Gamecocks recorded just 283 yards of total offense. LSU had 624 yards on offense and 29 first downs.
LSU led 17-10 at the half, but quickly scored twice in the third quarter to take a commanding 31-10 lead. South Carolina then scored with 5:02 left in the quarter on a 36-yard pass from Orth to wide receiver Jerell Adams to trim the deficit to 31-17.
Tigers running back Darrel Williams scored on a one-yard run to put the Tigers up 38-17 before the Gamecocks cut the lead to 38-24 just before the end of the quarter.
LSU scored the final touchdown of the game in the fourth quarter on a four-yard run by Guice to seal the 45-24 win with 13:15 left in the game.
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The Tigers also controlled the time of possession as they held the ball for 39:53. South Carolina had the ball for 20:07 in the game.
The LSU defense forced one South Carolina turnover in the game, and only allowed 24 points.
LSU would go on to defeat the Gamecocks 45-24 and move to 5-0 for the 2015 season.
This meeting marked the 10th straight win for LSU against South Carolina in the series.
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