Louisville vs. Indiana odds, picks and predictions

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The Louisville Cardinals (3-1) and the No. 15 Indiana Hoosiers (4-0) meet Wednesday at Imperial Arena in Nassau, Bahamas. Tip-off is scheduled for noon ET (ESPN). Let’s analyze BetMGM Sportsbook’s college basketball odds around the Louisville vs. Indiana odds, and make our expert college basketball picks and predictions.

The Cardinals have bounced back from a 77-55 loss against the Tennessee Volunteers on Nov. 9, Louisville’s only loss against a ranked team so far. Louisville is 1-2 against the spread (ATS) in the past 3 games, while cashing low in 3 of 4 outings, including against the Vols.

The Hoosiers have won all 4 games to date, with the highlight being an 87-71 win as an 8.5-point favorite against South Carolina on Nov. 16 at Assembly Hall. The Over cashed in that game, too, the only matchup this season against a power conference opponent.

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Louisville vs. Indiana odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college basketball odds. Lines last updated at 8:29 a.m. ET.

Moneyline (ML): Louisville +135 (bet $100 to win $135) | Indiana -165 (bet $165 to win $100)
Against the spread (ATS): Louisville +3.5 (-115) | Indiana -3.5 (-105)
Over/Under (O/U): 153.5 (O: -105 | U: -115)

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Louisville vs. Indiana picks and predictions

Prediction

Indiana 82, Louisville 74

Moneyline

INDIANA (-14]65) is worth playing as a moderate favorite in this battle in the Bahamas.

Louisville (+135) was outclassed by Tennessee at home on Nov. 9, and that’s hard to ignore. It was the only notable team the Cardinals have played, and they were embarrassed.

The Hoosiers are a much better team, and they’re more battle tested, too.

Against the spread

Back INDIANA -3.5 (-105), as they look to rebound from a non-cover against UNC Greensboro after a 69-58 win.

Still, the Hoosiers are 2-1 ATS in the past 3 games, including an emphatic 16-point victory over South Carolina on Nov. 16 in Bloomington. The different here is that Indiana has been tested, and it passed, while Louisville +3.5 (-115) failed miserably in its only previous game against a team of note.

Over/Under

OVER 153.5 (-105) is the lean, but go with a half-unit play at most.

Again, Indiana cashed high against South Carolina in the only game against a power conference team. It cashed low in games against SIU Edwardsville, Eastern Illinois and UNC Greensboro, but the Hoosiers defense will give up a little more against a better Cardinals offense.

Louisville has scored 93 or more points on 2 occasions, but be careful, as it has hit the Under in 3 of 4 outings. The defense has been good, but it did cough up 77 points in Tennessee, again, its only real test of the season to date.

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