In Week 3, we get our first AFC West divisional showdown as the Los Angeles Chargers (1-1) are on the road to face the Kansas City Chiefs (1-1). Kickoff is Sunday at 1 p.m. ET at Arrowhead Stadium. Below, we look at the Chargers at Chiefs odds and lines, and make our best NFL picks, predictions and bets.
The Chargers started the season with a hard-fought 20-16 win over the Washington Football Team on the road. QB Justin Herbert passed for 337 yards and the Chargers gained 424 total yards and their defense held Washington to only 259.
However, they turned the ball over twice so it was harder than it should have been. They followed that up with a 20-17 loss to the Dallas Cowboys, who kicked a 56-yard field goal as time expired for the win. L.A. had over 400 yards of offense again but Herbert threw two interceptions.
The Chiefs have been in two shootouts, outlasting the Cleveland Browns 33-29 in Week 1 and then losing 36-35 to the Baltimore Ravens in Week 2. Chiefs QB Patrick Mahomes has six touchdown passes in two games but the defense has allowed over 450 yards in both their games this season.
Chargers at Chiefs odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:17 a.m. ET.
- Money line: Chargers +230 (bet $100 to win $230) | Chiefs -300 (bet $300 to win $100)
- Against the spread (ATS): Chargers +6.5 (-105) | Chiefs -6.5 (-120)
- Over/Under (O/U): 54.5 (O: -108 | U: -112)
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Chargers at Chiefs key injuries
Chargers
- OLB Joey Bosa (foot) questionable
- CB Chris Harris (shoulder) out
- DE Justin Jones (calf) doubtful
Chiefs
- DE Chris Jones (wrist) questionable
- DE Frank Clark (hamstring) doubtful
- CB Charvarius Ward (quadriceps) questionable
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Chargers at Chiefs odds, lines, predictions and picks
Prediction
Chiefs 38, Chargers 35
Money line
PASS on the money line. The Chiefs have not lost consecutive games since October 2019 and have the second-best home record in the league at 16-5 since 2019.
The Chargers are 7-10 on the road in that same time frame, although they have won two of the last three matchups in Kansas City.
Believing the Chiefs will win the game, betting the money line at -300 just doesn’t bring the value.
That said, if you think the Chargers have a chance, it wouldn’t be a bad idea to lay down some change on the Chargers here gives you the best value of any wager here.
Against the spread
The Chargers are 1-1 ATS this season while the Chiefs have failed to cover the spread in either game this season and that follows last year’s 8-11 ATS season (including the postseason).
The Kansas City defense is going to keep the Chiefs from running away from teams, and this week they face an incredibly potent Chargers offense.
This will come down to the wire.
Take the CHARGERS +6.5 (-105).
Over/Under
The Chargers have piled up the yards this season but only have 37 points to show for it. The Chiefs have given up 65 points in two games.
Both of the Chiefs’ games have had totals in the 60s.
This is the week yards turn into points for the Chargers.
Take OVER 54.5 (-108).
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