Los Angeles Angels at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Los Angeles Angels at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Cleveland Guardians (20-11) welcome the Los Angeles Angels (11-20) to Progressive Field Friday. First pitch in the opener of the 3-game series is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Angels vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Angels won 4-3 in 2023

The Guardians lost to the Houston Astros 8-2 Thursday, dropping 2 of 3 in that series. Cleveland has lost 5 of its last 7, but won 5 in a row prior to that stretch. The Guardians are 22-9 against the spread (ATS) and 8-4 straight up at home.

The Angels started off the season 4-2, but have hit a wall. They are 2-11 over their last 13, having been swept in 2 of their last 4 series. They are coming off a 2-1 home loss to the Philadelphia Phillies Wednesday. Los Angeles is 15-16 ATS on the season.

Angels at Guardians projected starters

RHP Jose Soriano vs. RHP Tanner Bibee

Soriano (0-4, 4.76 ERA) makes his 5th start (7th appearance). He has a 1.37 WHIP, 5.6 BB/9 and 9.1 K/9 in 22 2/3 IP.

  • Last start: Loss, 1 2/3 IP, 4 ER, 3 H, 3 BB, 1 K in a 16-5 home loss vs. the Minnesota Twins Saturday
  • 2024 road splits: 0-1, 0.64 ERA, 14 IP, 1 ER, 5 H (0 HR), 10 BB, 15 K in 2 starts and 1 relief appearance
  • Career vs. Cleveland: 1-0, 0 ERA, 1 IP, 2.00 WHIP, 1 BB, 0 K in 1 relief appearance

Bibee (2-0, 3.45 ERA) makes his 7th start. He has a 1.31 WHIP, 3.4 BB/9 and 10.1 K/9 in 31 1/3 IP.

  • Last start: No-decision, 7 IP, 0 ER, 2 H, 0 BB, 9 K in 4-2 road win vs. Atlanta Braves Saturday
  • 2024 home splits: 1-0, 6.30 ERA, 10 IP, 7 ER, 11 H (2 HR), 5 BB, 10 K in 2 starts
  • Career vs. Los Angeles: 0-1, 1.84 ERA, 14 2/3 IP, 0.27 WHIP, 0 BB, 15 K in 2 starts

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Angels at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:56 a.m. ET.

  • Moneyline (ML): Angels +150 (bet $100 to win $150) | Guardians -178 (bet $178 to win $100)
  • Run line (RL)/Against the spread (ATS): Angels +1.5 (-146) | Guardians -1.5 (+122)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Angels at Guardians picks and predictions

Prediction

Guardians 6, Angels 3

Moneyline

PASS.

There’s not much value here either way. The Guardians are play far better but aren’t worth the expensive -178 tag. Meanwhile, the Angels (+150) are enticing but have struggled immensely as of late.

Run line/Against the spread

BET GUARDIANS -1.5 (+122).

The Guardians should have a major pitching advantage with Bibee on the mound. In his last 2 starts, the Guardians have allowed 4 total runs and covered the spread in both. Cleveland is 6-3 ATS as a home favorite, the best run-line record in that situation in the MLB.

The Angels are 9-10 ATS following a loss, which they are here. Los Angeles has lost 11 of its last 13 and has lost 8 of those 11 by more than 1 run. Given the plus-money odds here, take GUARDIANS -1.5 (+122).

Over/Under

LEAN OVER 8 (-115).

The Angels have gone Over in 4 of their last 5 games, allowing at least 5 runs in 6 of their last 7. The Angels have given up 26 runs in the last 3 games which Soriano has started on the mound.

The Guardians have gone Over in 3 of the last 4 games which Bibee has started and are 2-1 O/U in their last 3. They are 17-12-2 O/U on the season. Considering those trends, back OVER 8 (-115).

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