Iowa at Ohio State odds, picks and predictions

Analyzing Saturday’s Iowa Hawkeyes at Ohio State Buckeyes odds and lines, with college football expert picks, predictions and best bets.

The Iowa Hawkeyes (3-3, 1-2) and the Ohio State Buckeyes (6-0, 3-0) play Saturday at Ohio Stadium. Kickoff is scheduled for noon ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Iowa vs. Ohio State odds, and make our expert college football picks and predictions.

The Hawkeyes have had a bad taste in their mouths for the last 2 weeks since a 9-6 loss at Illinois. While Iowa did cover, and it is 3-1 against the spread (ATS) in the previous 4 games, it was the 4th time in 6 games the offense scored 14 or fewer points.

The Buckeyes blasted Michigan State last week by a 49-20 count, and it has 45 or more points in each of the last 5 games. The Over has cashed in each of the last 4 outings, and Ohio State is 3-0-1 ATS during the span.

Ohio State leads the country with 48.8 points per game (PPG) and ranks 2nd with 543.7 total yards per game. QB C.J. Stroud has completed 70.6% of his passes for 1,737 yards, 24 TDs and 3 INTs, while WR Marvin Harrison Jr. has hauled in 9 TDs.

Ohio State is No. 2 in the AFCA Coaches Poll powered by USA TODAY Sports.

Stream select live college football games and full replays: Get ESPN+

Iowa at Ohio State odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 10:22  p.m. ET.

  • Moneyline (ML): Iowa +2000 (bet $100 to win $2,000) | Ohio State -10000 (bet $10,000 to win $100)
  • Against the spread: Iowa +29.5 (-112) | Ohio State -29.5 (-108)
  • Over/Under (O/U): 49.5 (O: -115 | U: -107)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Iowa at Ohio State picks and predictions

Prediction

Ohio State 38, Iowa 6

Moneyline

There is never a reason to bet a money line over -200, unless it’s part of a multi-team parlay. Even then it’s a bad play. But there is no way you should even consider Ohio State (-10000), parlay or not.

AVOID.

Against the spread

OHIO STATE -29.5 (-108) is worth backing. While Iowa has a tremendous defense, and it has been shutting nearly everyone down, it won’t have the horses to make Stroud and company look bad. This is great offense vs. great defense, and it will be fun to watch — for a quarter or 2. Look for the Buckeyes to pull away in the 2nd half.

Over/Under

UNDER 49.5 (-107) is a risky play in games involving the Buckeyes, and the Over has hit in 4 in a row. The Hawkeyes defense will do a good job holding them down early, frustrating the Buckeyes before they solve Iowa later in the game. Ohio State won’t hit their averages in this game, and Iowa won’t even hit double digits.

Play our free daily Pick’em Challenge and win! Play now!

Want action on this game or any other NCAA football matchup? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

[mm-video type=playlist id=01fb7dafw2b08817yr player_id=none image=https://sportsbookwire.usatoday.com/wp-content/plugins/mm-video/images/playlist-icon.png]

Follow Kevin J. Erickson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1622]