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The Tennessee Titans (1-3) welcome the Indianapolis Colts (2-3) to Nissan Stadium Sunday for an AFC South clash. Kickoff is set for 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Colts vs. Titans odds, and make our expert NFL picks and predictions.
The Titans, who are 0-2 at home, are coming off their 1st win, beating the Miami Dolphins 31-12 on the road in Week 4. Tennessee had a bye in Week 5 so it’s had extra time to prepare for this game. Tennessee is 1-3 against the spread (ATS). The Titans have struggled offensively and average 19.8 points per game (20th). The last game was its 1st scoring over 17 points.
The Colts, who are 0-2 on the road, are banged up and numerous stars are likely to be game-time decisions. Indianapolis lost its 1st 2 games to the Houston Texans and Green Bay Packers before back-to-back home wins against the Chicago Bears and Pittsburgh Steelers. They lost 37-34 last week at the Jacksonville Jaguars. Indianapolis is 4-1 against the spread (ATS) and 1-1 ATS as a favorite.
The Colts swept the season series in 2023, winning 31-28 at Tennessee and 23-17 at home. Indianapolis leads the all-time series 37-22.
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Colts at Titans odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Friday at 11:21 a.m. ET.
- Moneyline (ML): Colts +120 (bet $100 to win $120) | Titans -145 (bet $145 to win $100)
- Against the spread (ATS): Colts +2.5 (-105) | Titans -2.5 (-115)
- Over/Under (O/U): 43 (O: -110 | U: -110)
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Colts at Titans key injuries
Colts
- WR Josh Downs (toe) questionable
- DE Kwity Paye (quadricep) questionable
- WR Michael Pittman Jr. (back) questionable
- QB Anthony Richardson (oblique) questionable
- T Braden Smith (knee, ankle) questionable
- RB Jonathan Taylor (ankle) out
Titans
- S Jamal Adams (hip) questionable
- DT Keondre Coburn (knee) questionable
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Colts at Titans picks and predictions
Prediction
Titans 24, Colts 23
Moneyline
BET TITANS (-145).
The Colts defense has been annihilated over the last few weeks. They allowed 37 points to the Jaguars in Week 5 and 24 to the Steelers in Week 4. Indianapolis is allowing opponents an average of 419 yards per game (262 passing, 157 rushing).
The Titans have playmakers despite having struggled through the 1st few weeks. They put up 31 points on Miami and took on 2 playoff-contending teams in the New York Jets and Packers at home. Indianapolis will likely be without its leading receiver and running back.
Those absences along with the Colts’ disappointing road record make Tennessee the play here. Back TITANS (-145).
Against the spread
PASS.
The spread is reasonable, and it could be played instead. The preferred route is to take some of the risk out of the equation and just play the home side to win outright.
Over/Under
BET OVER 43 (-110).
Both teams have trended toward more points than less, and both have also struggled defensively. The Titans are 2-1-1 O/U this season and 2-0 O/U in their last 2 games. They have allowed 24 points or more in 3 of 4 games as well.
The Colts are 2-0 O/U in their last 2 as well and are 3-2 O/U on the season. They have scored 21 points or more in 3 straight games and have allowed 30.5 points per game in their last 2.
With those trends in mind, play OVER 43 (-110).
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