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The Indianapolis Colts (3-2-1) visit Nissan Stadium Sunday to face the Tennessee Titans (3-2). Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Titans odds, and make our expert NFL picks and predictions.
Last week, the Colts beat the Jacksonville Jaguars 34-27 as 1-point favorites. They started slow, trailing 21-19 after 3 quarters, but outscored the Jaguars 15 to 6 in the final quarter. QB Matt Ryan‘s play helped make up for the absence of RB Jonathan Taylor (ankle). Ryan threw for 389 yards and 3 touchdowns, completing 42 of 58 pass attempts. His top receiver was WR Michael Pittman Jr., who had 13 receptions for 134 yards. Seven receivers who caught a ball from Ryan had at least 3 receptions each. The defense finished with 4 sacks and forced a fumble in the win.
The Titans are coming off a bye week, previously winning at the Washington Commanders 21-17 in Week 5. In that game, RB Derrick Henry had 28 carries for 102 yards and 2 TDs, while QB Ryan Tannehill went 15 of 25 for 181 passing yards and a TD. Seven Titans had at least 1 reception. Tennessee was outgained in total yards 385 to 241, but Henry proved to be the X-factor. The defense had 3 sacks and forced an interception in the victory. Expect the Titans’to utilize Henry just as much Sunday coming off of a week of rest.
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Colts at Titans odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:08 a.m. ET.
- Moneyline (ML): Colts +117 (bet $100 to win $117) | Titans -140 (bet $140 to win $100)
- Against the spread (ATS): Colts +2.5 (-103) | Titans -2.5 (-117)
- Over/Under (O/U): 42.5 (O: -108 | U: -112)
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Colts at Titans key injuries
Colts
- LB Shaquille Leonard (concussion, nose, back) out
- DE Kwity Paye (ankle) out
Titans
- LB Zach Cunningham (elbow) out
- OL Nate Davis (foot) out
- WR Kyle Phillips (hamstring) questionable
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Colts at Titans picks and predictions
Prediction
Titans 20, Colts 17
Moneyline
TAKE THE TITANS (-140).
Coming off a bye week, expect Tennessee to be at full strength, giving Henry the necessary rest to continue his dominant season thus far. Coach Mike Vrabel will have the team ready to compete at home against a Colts squad that has yet to prove itself.
Against the spread
LEAN TITANS -2.5 (-117).
Scoring 92% of the time they are in the red zone and only giving up points 50% of the time the opposing offense is in the red zone is a recipe for success for the Titans. With offensive weapons in WR Robert Woods and Henry, they have the ability to get into scoring range quickly. Barring a massive game in Taylor’s return from injury, lean Titans ATS.
Furthermore, the Titans are 6-0 ATS in their last 6 games in October and the favorite is 14-6 ATS in these teams’ last 20 meetings. The Colts are also 0-4 ATS in the last 4 meetings between these two.
Over/Under
Bet the UNDER 42.5 (-112).
All the trends in this one point toward taking the Under.
The Under is 6-0 in the Colts’ last 6 road games, 4-0 in their last 4 on grass, and 4-0 in their last 4 against a team with a winning record.
For the Titans, the Under is 8-1 in their last 9 games on grass and 4-0 in their last 4 games following a straight-up win.
The Under is 5-1 for the Colts this season and 3-2 for the Titans. Expect a run-heavy game between Taylor and Henry which will accumulate to the clock ticking away constantly.
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