Indianapolis Colts at Jacksonville Jaguars odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Jacksonville Jaguars odds and lines, with expert NFL picks and predictions.

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Indianapolis Colts (2-2) face the Jacksonville Jaguars (0-4) Sunday. Kickoff from EverBank Stadium is scheduled for 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.

Both teams enter Week 5 with big red flags. Colts QB Anthony Richardson is not living up to his preseason expectations while the entire Jags offense can say the same thing.

Jacksonville hasn’t scored more than 20 points this season and QB Trevor Lawrence hasn’t been so hot. In their matchup against the Houston Texans, he was 18for-33 for just 169 yards, and they converted 3rd down 4 times in 12 attempts. They led late in the 4th quarter and could not secure the win, falling 24-20 to drop to 0-4.

Indianapolis led the entire game against the Pittsburgh Steelers despite Richardson leaving early with a hip injury. QB Joe Flacco came in and played like he did last year, which won him the Comeback Player of the Year. WR Michael Pittman Jr. was the top receiver on the Colts with 6 catches for 113 yards, helping the Colts win 27-24.

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Colts at Jaguars odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 2:20 p.m. ET.

  • Moneyline (ML): Colts +140 (bet $100 to win $140) | Jaguars -165 (bet $165 to win $100)
  • Against the spread (ATS): Colts +3 (-105) | Jaguars -3 (-115)
  • Over/Under (O/U): 45.5 (O: -110 | U: -110)

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Colts at Jaguars key injuries

Colts

  • C Ryan Kelly (neck) questionable
  • CB Kenny Moore (hip) out
  • DE Kwity Paye (quad) out
  • QB Anthony Richardson (oblique) questionable
  • OT Braden Smith (knee) questionable
  • RB Jonathan Taylor (ankle) out

Jaguars

  • TE Evan Engram (hamstring) questionable
  • DE Josh Hines-Allen (concussion) questionable
  • LB Devin Lloyd (knee) questionable
  • S Darnell Savage Jr. (quad) questionable
  • S Daniel Thomas (hamstring) questionable

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Colts at Jaguars picks and predictions

Prediction

Colts 34, Jaguars 29

Moneyline

The Colts have started out slow, but I don’t think the Jaguars will pose much of a problem. Indianapolis posts the 6th-highest yards per pass (8 yards), while Jacksonville’s defense allows the 3rd worst (8 yards).

The Colt’s main liability is their run defense, which they rank worst in rush attempts a game (37.8). But the Jaguars don’t lean on their run game, rushing the 4th fewest times per game in the league (22).

I like the Colts at plus-money, but I will actually PASS here and opt for the spread.

Against the spread

Home favorites haven’t been as dominate this season against they spread, posting a 17-25-1 record. And with Jacksonville a favorite despite their winless record, I will take the Colts with the points, whether its Richardson or Flacco under center.

LEAN COLTS +3 (-105).

Over/Under

Both teams are under pressure to score in this game. And lucky for them, this is a perfect get-right game. The Colts lead the league in opponent yards per game (399.8) while the Jaguars are 3rd-worst (380).

On top of that their red zone defense is nearly as bad. Jacksonville allows a 75% touchdown rate in the red zone while Indianapolis is only slightly better with 69.2% red zone defense.

BET OVER 45.5 (-110).

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