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The Indianapolis Colts (3-2) and Jacksonville Jaguars (3-2) meet Sunday at EverBank Stadium. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze BetMGM Sportsbook’s lines around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.
The Colts, having won 3 of their last 4, picked up a 23-16 home win over the Tennessee Titans as 2.5-point road underdogs. The Under (43.5) cashed in. They finished the game without rookie QB Anthony Richardson, who got hurt and has since been placed on injured reserve.
The Jaguars spent the last 2 weeks in London, picking up 2 wins. Last week, they upset the Buffalo Bills 25-20 as 5.5-point underdogs. The Under (48.5) hit in the win. They were the road team in that game. The week prior, they beat the Atlanta Falcons 23-7, covering as 3-point “home” favorites.
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Colts at Jaguars odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 12:35 p.m. ET.
- Moneyline (ML): Colts +165 (bet $100 to win $165) | Jaguars -200 (bet $200 to win $100)
- Against the spread (ATS): Colts +4.5 (-115) | Jaguars -4.5 (-105)
- Over/Under (O/U): 44 (O: -110 | U: -110)
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Colts at Jaguars key injuries
Colts
- TE Mo Alie-Cox (concussion) available
- C Ryan Kelly (ankle/foot) questionable
- T Braden Smith (foot, wrist, hip) out
Jaguars
- LB Devin Boyd (thumb) questionable
- WR Zay Jones (knee) out
- OL Walker Little (knee) out
Colts at Jaguars picks and predictions
Prediction
Jaguars 27, Colts 20
Moneyline
The Jaguars already beat the Colts 31-21 in Indianapolis in Week 1. They have won 2 straight games but have not won yet in their home stadium this season.
The Colts are 1-0 this season with Gardner Minshew starting at quarterback. They are 2-0 on the road this season. In their 3 wins this season, they have not allowed more than 20 points.
The Jaguars have averaged 26.3 points per game in their 3 wins.
The Jags must overcome being without Jones and Little on offense. Their defense held Buffalo to only 20 points and the Falcons to only 7.
The Jaguars should win, but at -200 odds, PASS on the moneyline.
Against the spread
Both teams are 3-2 ATS this season, covering the spread in their 3 wins and failing to do so in their 2 losses.
The Colts have not lost by fewer than 6 points. The Jaguars’ 3 wins have been by at least 5 points.
Jacksonville is 2-1 ATS when favored. The Colts have been the underdogs in every game this season.
BET JAGUARS -4.5 (-105).
Over/Under
The Week 1 matchup between the 2 teams had 52 total points.
Indy’s 2 losses have had 52 total points each.
Two of Jacksonville’s 3 wins have had at least 45 points.
BET OVER 44 (-110).
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