Indianapolis Colts at Jacksonville Jaguars odds, picks and prediction

Analyzing Sunday’s Indianapolis Colts at Jacksonville Jaguars odds and lines, with expert NFL picks, predictions and best bets.

On Sunday, the Indianapolis Colts (9-7) travel to Florida to take on the Jacksonville Jaguars (2-14). Kickoff at EverBank Field is slated for 1 p.m. ET. Below, we look at the Colts vs. Jaguars odds and lines, and make our best NFL picks, predictions and bets.

The Colts are entering this game in a must-win scenario. If the Colts lose, they’re more than likely out (they could still get in with a Raiders/Chargers win and a Steelers/Ravens tie). Basically, they need to win.

Indy has been better than preseason expectations, covering 10 of its 16 games. The Jags, on the other hand, have had a fiasco of a season and have covered just 4 times this season.

Jacksonville’s star RB James Robinson has been out after sustaining a season-ending injury. With QB Trevor Lawrence set to start, the Jags have failed to cover 7 straight games including twice as double-digit underdogs.

Colts at Jaguars odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:30 a.m. ET.

  • Money line: Colts -1200 (bet $1200 to win $100) | Jaguars +700 (bet $100 to win $700)
  • Against the spread (ATS): Colts -14.5 (-108) | Jaguars +14.5 (-112)
  • Over/Under (O/U): 43.5 (O: -110 | U: -110)

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Colts at Jaguars key injuries

Colts

  • CB Xavier Rhodes (hamstring) out
  • DT DeForest Buckner (knee) questionable

Jaguars

  • TE James O’Shaughnessy (knee) out
  • TE Dan Arnold (knee) questionable

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Colts at Jaguars odds, lines, predictions and picks

Prediction

Colts 31, Jaguars 10

Money line

PASS on the money line. A -1200 in the NFL has no value. Similarly, the Colts are in a must-win scenario and are the far better team, giving the Jaguars +700 also little value.

Against the spread

BET on the COLTS -14.5 (-108).

While the Colts are a bona fide playoff contender, this is more a fade on the Jags. The two times in the past two months that they’ve been double-digit underdogs, they lost by 30 and 40.

With an atrocious run defense, the Colts, who have the league’s rushing yards leader in Jonathan Taylor, should be able to have their way. The Jags rank 25th in opponents’ rushing yards per game.

They also rank dead last in turnovers. Indy ranks 2nd in defensive turnovers, so it’ll more than be giving great field position a couple of times. With that in mind, I’d back the COLTS -14.5 (-108).

Over/Under

“LEAN” to the UNDER 43.5 (-110). The Jags haven’t been able to move the ball for the better part of the season, and they’ve covered the Over just 5 times.

Jacksonville ranks at the bottom of the league in points per game and will face a Colts defense that knows the stakes this game has.

With that in mind, I’d lean the Under as the Colts should heavily limit the Lawrence-led Jags.

Also see: All Week 18 odds and lines

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