Indianapolis Colts at Denver Broncos odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Denver Broncos odds and lines, with expert NFL picks and predictions.

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The Indianapolis Colts (6-7) visit the Denver Broncos (8-5) on Sunday. Kickoff from Empower Field at Mile High is scheduled for 4:25 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Colts vs. Broncos odds, and make our expert NFL picks and predictions.

The Colts come off a bye week having won 2 of their last 3 games after beating the Patriots 25-24 in Week 13 while failing to cover as 2.5-point road favorites. QB Anthony Richardson threw a 3-yard TD pass with 12 seconds left and ran a successful 2-point conversion for the win.

Denver comes off its bye week on a 3-game winning streak, the last a 41-32 Monday night victory inWeek 13 over the Cleveland Browns, covering as a 6.5-point home favorite. QB Bo Nix went 18 of 35 for 294 yards with a TD and 2 INTs.

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Colts at Broncos odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 8:44 p.m. ET.

  • Moneyline (ML): Colts +165 (bet $100 to win $165) | Broncos -200 (bet $200 to win $100)
  • Against the spread (ATS): Colts +4 (-105) | Broncos -4 (-115)
  • Over/Under (O/U): 44 (O: -110 | U: -110)

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Colts at Broncos key injuries

Colts

  • TE Mo Alie-Cox (hip) questionable
  • LB Jaylon Carlies (fibula, shoulder) questionable
  • WR Josh Downs (shoulder) questionable
  • WR Ashton Dulin (ankle) out
  • Ryan Kelly (knee) questionable
  • Braden Smith (personal) out

Broncos

  • CB Riley Moss (knee) out

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Colts at Broncos picks and predictions

Prediction

Broncos 27, Colts 20

Moneyline

PASS.

There is minimal value on a streaking Denver (-200) team to win on Sunday.

Against the spread

BET DENVER -4 (-115).

The Broncos have covered in 4 straight games and in 8 of their last 10 contests, including each of their last 6 games as favorites. The Colts have failed to cover in 4 of their last 5 outings, including back-to-back games,  while losing 4 of their last 6.

Over/Under

BET OVER 44 (-110).

The Colts have scored 20 or more points in 3 of their last 4 games and in 7 of their last 10 while allowing 24 or more points in 4 straight. They have hit the Over in 3 of their last 4 games.

The Broncos have hit the Over in 7 of their last 10 contests, including back-to-back games. They have scored 29 or more points in 3 straight games and have allowed 19 or more points in back-to-back games.

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