The Houston Astros (28-20) and the Milwaukee Brewers (26-22) wrap up a 3-game interleague series Wednesday at American Family Field. First pitch is scheduled for 1:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Brewers odds and make our expert MLB picks and predictions for the best bets.
Season series: Series tied 1-1
The Astros’ 8-game win streak came to a crashing halt Tuesday as the Brewers posted a 6-0 victory behind RHP Colin Rea. The Astros were held to just 5 hits, and they were shut out for the 1st time since a 2-0 loss at home against the San Francisco Giants on May 2. Houston had won the series opener 12-2 on Monday.
The Brewers bounced back from the 10-run drubbing for their 1st shutout win since a 1-0 victory on April 16 at the San Diego Padres. Milwaukee is now 12-8 in interleague play, the most wins in interleague play by any team in the majors.
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Astros at Brewers projected starters
RHP Brandon Bielak vs. RHP Adrian Houser
Bielak (1-1, 2.89 ERA) makes his 4th start and 5th overall appearance. He has a 1.77 WHIP, 3.9 BB/9 and 9.2 K/9 in 18 2/3 innings.
- Last start: Win, 5 IP, 1 ER, 5 H, 3 BB, 9 K in a 5-1 home win vs. the Oakland Athletics Friday
- Road splits this season: 0-1, 2.79 ERA (9 2/3 IP, 3 ER), .419 OBA in 2 starts
Houser (0-0, 3.07 ERA) makes his 4th start. He has a 1.50 WHIP, 1.8 BB/9 and 6.8 K/9 in 14 2/3 IP innings.
- Last start: No-decision, 6 IP, 0 ER, 4 H, 1 BB, 4 K in a 1-0 road loss win vs. the Tampa Bay Rays Friday
- Home splits this season: No-decision, 3 ER, 8 H, 1 BB and 2 K across 4 IP in his only home start vs. Kansas City Royals May 13
Astros at Brewers odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:21 a.m. ET.
- Moneyline (ML): Astros -110 (bet $110 to win $100) | Rays -110 (bet $105 to win $100)
- Run line (RL)/Against the spread (ATS): Astros -1.5 (+150) | Brewers +1.5 (-185)
- Over/Under (O/U): 9 (O: -115 | U: -105)
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Astros at Brewers picks and predictions
Prediction
Astros 6, Brewers 5
Moneyline
The ASTROS (-110) are worth a look in the interleague series finale, although we should see plenty of fireworks early on with 2 very giving pitchers.
Still, despite Tuesday’s loss, the Astros are 5-2 in the last 7 interleague road games, while going 8-4 in the last 12 road games against a right-handed starting pitcher.
The Brewers (-110) are just 3-5 in the last 8 games against winning teams, while going 2-4 in the last 6 games overall.
Run line/Against the spread
The Brewers +1.5 (-185) will cost you nearly 2 times your potential return, and that’s quite expensive if you require a little bit of insurance on the home team. If you like Milwaukee, just play it straight up.
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Over/Under
The OVER 9 (-115) is a solid option, although the Under has been the trend for both teams lately.
While the Under is 6-2 in the last 8 road games for the Astros, the Over is 5-1 in the last 6 interleague games, while going 26-10-1 in the past 37 meetings overall in this series.
The Over is 5-1 in the last 6 interleague games for the Brewers, too, while cashing at a 5-1 clip in the last 6 in Game 3 of a series.
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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