Houston Astros at Cincinnati Reds odds, picks and predictions

Analyzing Thursday’s Houston Astros at Cincinnati Reds odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (75-64) and Cincinnati Reds (67-73) meet for the finale of a 3-game series Thursday. First pitch from Great American Ball Park is set for 1:10 p.m. ET (ESPN+). Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Reds odds and make our expert MLB picks and predictions for the best bets.

Season series: Cincinnati leads 2-0

After a 5-3 win in the Tuesday opener, Cincinnati routed Houston 12-5 Wednesday while covering as a +125 home underdog. The Reds erupted for 9 runs in the 1st inning in winning its 3rd straight. RHP Nick Martinez picked up the win (5 1/3 IP, 1 ER, 6 H, 3 BB, 7 K).

Rookie RHP Spencer Arrighetti took the loss as he allowed an astounding 9 ER in 2/3 IP (6 H, 3 BB, 0 K). It was the the shortest outing, and most runs he’s allowed, in his 24-game career.

Astros at Reds projected starters

RHP Hunter Brown vs. RHP Rhett Lowder

Brown (11-7, 3.55 ERA) makes his 27th start. He has a 1.29 WHIP, 3.3 BB/9 and 9.5 K/9 in 147 IP.

  • Last start: No-decision, 6 2/3 IP, 0 ER, 2 H, 2 BB, 4 K in a 6-3 win vs. Kansas City Royals Thursday
  • First time facing Cincinnati

Lowder (0-1, 2.25 ERA) makes his 2nd career start. He has a 1.50 WHIP, 9.0 BB/9 and 13.5 K/9 in 4 IP.

  • MLB debut: Loss, 4 IP, 1 ER, 2 H, 4 BB, 6 K in a 14-0 loss vs. Milwaukee Brewers Friday
  • Has 6-4 record with 3.64 ERA in 22 minor league games

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Astros at Reds odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:41 p.m. ET.

  • Moneyline (ML): Astros -150 (bet $150 to win $100) | Reds +125 (bet $100 to win $125)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+105) | Reds +1.5 (-130)
  • Over/Under (O/U): 9 (O: -115 | U: -105)

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Astros at Reds picks and predictions

Prediction

Reds 3, Astros 1

Moneyline

LEAN REDS (+125).

Cincinnati has won 3 straight home games while Houston is 1-4 in its last 5 on the road.

The Reds have also been dominant in their recent matchups vs. Houston, going 8-2 in the last 10. They have won the last 4 meetings in Cincinnati.

Run line/Against the spread

PASS.

Cincinnati is slightly better ATS (78-62) than Houston (71-68), but that advantage is not big enough to make me advise taking this bet over the moneyline. You can divvy up units between this bet and the moneyline, but I like the moneyline more than this play.

Over/Under

BET UNDER 9 (-105).

The Under is 3-1-1 in Houston’s last 5 road games and is 2-1 in Cincinnati’s last 3 games. The Under has also hit in 4 of the last 5 Astros-Reds meetings in Cincinnati and 6-4 in the last 10 matchups overall.

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