Houston Astros at Chicago White Sox odds, picks and predictions

Analyzing Wednesday’s Houston Astros at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (33-40) face the Chicago White Sox (20-54) for the second game of a 3-game series Wednesday. First pitch from Guaranteed Rate Field is at 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: White Sox lead 1-0

RHP Jonathan Cannon scattered 7 hits in 8 2/3 scoreless innings and the White Sox shut out the Astros 2-0 in the series opener Tuesday.

The Astros have alternated wins and losses over their last 6 games and are 3-5 in their last 8.

The White Sox have won 3 of their last 5 games but are 6-24 in their last 30.

Astros at White Sox projected starters

RHP Hunter Brown vs. LHP Garrett Crochet

Brown (3-5, 5.00 ERA) makes his 14th start and 15th appearance. He has a 1.43 WHIP, 3.8 BB/9 and 10.0 K/9 in 68 1/3 innings.

  • Last start: Win, 7 IP, 0 R, 5 H, 0 BB, 9 K in 4-0 home victory over Detroit Tigers Friday
  • Has not allowed a run in last 2 starts (13 IP)

Crochet (6-5, 3.16 ERA) makes his 16th start. He has a 0.90 WHIP, 2.1 BB/9 and 12.6 K/9 in 82 2/3 innings.

  • Last start: No-decision, 7 IP, 1 ER, 2 H, 2 BB, 13 K in 3-2 road win over Seattle Mariners Thursday
  • Is 5-1 with 1.13 ERA over last 8 starts (48 IP)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Astros at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:33 a.m. ET.

  • Moneyline (ML): Astros -120 (bet $120 to win $100) | White Sox +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros -1.5 (+145) | White Sox +1.5 (-175)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Astros at White Sox picks and predictions

Prediction

White Sox 4, Astros 2

Moneyline

What a fun matchup with the starters.

Crochet has been dominant for a month and a half. Brown hasn’t allowed a run in his last 2 starts and has a 2.58 ERA over his last 8 outings.

The Astros are bad on the road at 14-21, but the Sox aren’t good at home at 13-23.

But the White Sox have held opponents to 2 or fewer runs in 4 of their last 6 games.

I’m riding the hot hand with Crochet, as the Sox are 6-2 in his last 8 outings.

BET WHITE SOX (+100).

Run line/Against the spread

Expecting a White Sox win, it wouldn’t make sense to bet them to cover the +1.5 at -175.

Now, as 9 of Chicago’s last 10 wins have been by more than 1 run and 5 of the last 6 wins with Crochet starting have been by 2 or more runs, you can really add to your winnings by laddering an alternate spread.

BET ALTERNATE SPREAD WHITE SOX -1.5 (+190).

Over/Under

Five of Crochet’s last 6 starts have not reached 8 total runs. Brown’s last 5 starts have all had 7 or fewer total runs.

This should be a low-scoring game.

BET UNDER 7.5 (-120).

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