Houston Astros at Chicago White Sox odds, picks and predictions

Analyzing Saturday’s Houston Astros at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

The Houston Astros (20-18) continue their series on the road against the Chicago White Sox (13-27) for the 2nd of their 3-game series on Saturday night. First pitch is 7:15 p.m. ET at Guaranteed Rate Field. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Astros lead 3-2.

The Astros took the series opener Friday 5-1 after a rain delay of more than 2 hours. OF Ryan Tucker’s 2-run double in the 5th gave the Astros a 2-1 lead and they never looked back. RHP J.P. France picked up his 1st win of the year with 6 2/3 scoreless innings. It was the Astros’ 3rd win in a row.

The White Sox have lost 3 in a row and 4 of their last 5 games. They have scored 4 combined runs in the losing streak.

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Astros at White Sox projected starters

RHP Brandon Bielak vs. RHP Dylan Cease

Bielak (0-1, 4.15 ERA) makes his 2nd start of the season and 3rd appearance. He has a 1.96 WHIP, 5 BB and 6 K through 8 2/3 IP.

  • Lost his last (and first) start 3-1 to Seattle, allowing 3 R (2 ER), 10 H and 2 BB in 4 2/3 IP
  • Has 3.18 ERA in 3 relief appearances vs. Chicago (5 2/3 IP)

Cease (2-2, 5.58 ERA) makes his 9th start. He has a 1.51 WHIP, 4.5 BB/9 and 10.9 K/9 through 40 1/3 IP.

  • 0-2 with 10.93 ERA in last 3 starts (14 IP)
  • 0-3 with 5.13 ERA in 5 career starts vs. Astros

Astros at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:35 a.m. ET.

  • Moneyline (ML): Astros +105 (bet $100 to win $105) | White Sox -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros +1.5 (-185) | White Sox -1.5 (+150)
  • Over/Under (O/U): 9 (O: +100 | U: -120)

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Astros at White Sox picks and predictions

Prediction

Astros 5, White Sox 3

Moneyline

It is interesting to see the Astros with positive odds in this game on the moneyline. They are 12-7 on the road this season and the White Sox are 6-11 at home and are 3-6 in their last 9 games.

The Astros have won 3 in a row. They have beaten the White Sox in 5 of the last 7 meetings.

BET ASTROS (+105).

Run line/Against the spread

PASS.

Betting the Astros to simply cover isn’t worth the -185 odds.

The White Sox only have 2 wins of 2 or more runs in their last 9 games.

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Over/Under

Only 1 of the 5 games the teams have played this season has had more than 9 total runs.

The Astros have not scored more than 5 runs in their last 6 games and also in 8 of their last 9.

The White Sox have not scored more than 3 in their last 3.

BET UNDER 9 (-120).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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