The 49ers injury situation was supposed to get better during the second half of the season. It’s gone the other direction.

San Francisco faces the Cardinals on Sunday, a team they snuck past 28-25 two weeks ago. This time they’ll likely do so without tight end George Kittle, running back Matt Breida, and kicker Robbie Gould. All three are officially ‘doubtful’ on the Week 11 injury report after missing practice all week.

Kittle is working through ankle and knee injuries he suffered in Week 9 against Arizona. Breida is resting an ankle ailment he aggravated in the Week 10 loss to the Seahawks, and Gould is nursing a sore quad he hurt in practice leading up to the Seattle game.

The good news is cornerback Ahkello Witherspoon is expected to return, although he’s officially questionable. Witherspoon has been out since spraining his foot in Week 3. Wide receiver Emmanuel Sanders suffered a rib cartilage injury against the Seahawks. He’s questionable, but told reporters he’s going to try and play, per Matt Barrows of the Athletic.

Here is the full injury report:

Out

DT D.J. Jones (groin)
OT Joe Staley (finger)

Doubtful

RB Matt Breida (ankle)
K Robbie Gould (right quadricep)
TE George Kittle (knee, ankle)

Questionable

LB Azeez Al-Shaair (concussion)
CB Ahkello Witherspoon (foot, quad)
RB Raheem Mostert (knee)
WR Dante Pettis (back)
WR Emmanuel Sanders (ribs)