Former Wisconsin running back Isaac Guerendo is expected to miss multiple weeks of San Francisco 49ers training camp with a hamstring injury, according to ESPN’s Adam Schefter.
Just months after being selected No. 129 overall pick in the fourth round of the 2024 NFL draft by the 49ers, Guerendo will now miss significant time with the season fast approaching.
The Indiana native became the second San Francisco rookie to suffer a hamstring injury, joining former Florida wide receiver Ricky Pearsall.
Guerendo totaled 27 appearances while representing the Badgers from 2018-22. He served as Wisconsin’s primary reserve running back in 2022 and registered 385 yards and five touchdowns, plus 17 passes for 115 yards and a touchdown.
The veteran elected to transfer to Louisville after the 2022 season. He went on to rush for 810 yards and 11 touchdowns on 132 carries with the Cardinals in 2023.
49ers DE Drake Jackson is out for training camp, at a minimum, as he tries to recover from a knee injury.
49ers rookie RB Isaac Guerendo is expected to be sidelined multiple weeks due to a hamstring injury.
— Adam Schefter (@AdamSchefter) July 29, 2024
Prior to the incident, Guerendo was No. 4 on San Francisco’s running back depth chart behind all-world playmaker Christian McCaffrey, Elijah Mitchell and Jordan Mason.
Given his position in the 2024 draft, Guerendo has a strong likelihood of landing on the 49ers’ final 53-man roster in August despite the injury. But it remains unclear how long the playmaker will be sidelined.