First look: USC at Colorado odds and lines

Looking at Saturday’s USC at Colorado college football odds, lines and trends. Here’s what you need to know.

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The USC Trojans (4-0, 2-0 Pac-12) travel to meet the Colorado Buffaloes  (3-1, 0-1) on Saturday at Folsom Field in Boulder. Kickoff is scheduled for noon ET (FOX). Below, we look at USC vs. Colorado odds from FanDuel Sportsbook. Also see: SportsbookWire’s college football picks and predictions.

The Trojans started a bit slow on the road against Arizona State, but USC did enough to earn the 42-28 win. It was actually USC’s lowest-scoring game of the season, as it had scored 56 or more points in the 1st 3 outings. The Over is 3-1 in 4 games for the Trojans.

The Buffaloes opened the season with 3 consecutive victories, capturing the imagination of fans everywhere in the Rocky Mountain State. Colorado, and  coach Deion Sanders, have certainly been polarizing. Many discounted the 3-0 start due to ease of schedule, and looked forward to seeing how the Buffaloes did against Oregon in the Pac-12 opener. The result against the Ducks was not good, as CU fell 42-6 and out of the top 25.

USC is No. 6 in the US LBM Coaches Poll powered by USA TODAY Sports.

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USC at Colorado odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 12:29 p.m. ET.

  • Moneyline (ML): USC -2800 (bet $2,800 to win $100) | Colorado +1160 (bet $100 to win $1,160)
  • Against the spread (ATS): USC -25.5 (-110) | Colorado +25.5 (-110)
  • Over/Under (O/U): 721.5 (O: -115 | U: -105)

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2023 betting stats

  • ML: USC 4-0 | Colorado 3-1
  • ATS: USC 2-2 | Colorado 2-2
  • O/U: USC 3-1 | Colorado 2-2

USC at Colorado head-to-head

The Buffaloes probably won’t be sad to move along to the Big 12, while the Trojans head for the Big Ten in 2024. In 16 previous meetings, USC has ended up winning each of the games, including a 55-17 win at the Los Angeles Memorial Coliseum on Nov. 11 last season. In the most recent meeting in Boulder, USC picked up a 37-14 win.

USC has posted victories of 11 or more points in 4 of the past 5 in this series since Nov. 11, 2017. Only 4 of the 16 all-time meetings have been 1-score games, too. The Over has cashed in the past 3 in the series, while going 6-3 in the past 9 encounters overall.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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