First look: Tennessee Titans at Indianapolis Colts odds and lines

Looking at Sunday’s Tennessee Titans at Indianapolis Colts Week 8 NFL odds, lines and trends. Here’s what you need to know.

The Tennessee Titans (5-2) are on the road in Week 8 and face the Indianapolis Colts (3-4) in an AFC South showdown. Kickoff is 1 p.m. ET at Lucas Oil Stadium Sunday afternoon. Below, we look at the Titans vs. Colts odds and lines; check back for our NFL picks and predictions.

The Titans won their third straight game Sunday, defeating the Kansas City Chiefs 27-3. They are in control of their division. They held QB Patrick Mahomes without a touchdown pass and kept one of the top offenses in the league out of the end zone. They are led by the NFL’s leading rusher in RB Derrick Henry, whose 191 rushing attempts, 869 rushing yards and 10 rushing touchdowns all lead the NFL.

The Colts have bounced back from an 0-3 start to the season to win three of their last four games. They defeated the San Francisco 49ers 30-18 Sunday night. QB Carson Wentz has 11 touchdowns and only one interception. After leading the NFL in picks in 2020, he now has the league’s lowest interception percentage at 0.5%.

Titans at Colts odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 7:45 a.m. ET.

  • Money line: Titans -125 (bet $125 to win $100) | Colts +102 (bet $100 to win $102)
  • Against the spread (ATS): Titans -1.5, -115 (bet $115 to win $100) | Colts +1.5, -105 (bet $105 to win $100)
  • Over/Under (O/U): 49.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)

Also see: Betting 101

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2021 betting stats:

  • ML: Titans 5-2 | Colts 3-4
  • ATS: Titans 5-2 | Colts 5-2
  • O/U: Titans 4-3 | Colts 4-3

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Titans at Colts head-to-head

This will be the 55th time they face one another dating back to 1970. The Colts lead the all-time series 35-19. At one point, from 2011-2016, the Colts beat the Titans 11 straight times and 16 out of 17.

The two teams already met once this season, with Tennessee picking up a 25-16 win at home. The Titans have won three of the last four games between them. Wentz is 0-2 in two career starts against the Titans.

Titans QB Ryan Tannehill is 4-4 in eight career starts against the Colts.

Also see: All Week 8 odds and lines

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