First look: Stanford at Notre Dame odds and lines

Looking at Saturday’s Stanford at Notre Dame college football odds, lines and trends. Here’s what you need to know.

The Notre Dame Fighting Irish (3-2) welcome the Stanford Cardinal (1-4) Saturday. Kickoff from Notre Dame Stadium is set for 7:30 p.m. ET. Below, we look at Stanford vs. Notre Dame odds from Tipico Sportsbook; check back for all our college football picks and predictions.

The Fighting Irish, after losing in the first 2 weeks of the season to Ohio State and Marshall, have since won 3 straight games. They’ve taken down California, UNC and BYU.

QB Drew Pyne is the team’s leader with 9 touchdowns and 2 interceptions on the season. Their defense is also allowing just 23.2 points per game, No. 52 of 131 FBS programs.

As for Stanford, it is led by QB Tanner McKee. McKee has thrown 10 touchdowns and 5 interceptions. At 6-foot-6, McKee is a quality NFL prospect, having thrown for 1,249 passing yards this season.

The Cardinals have just 1 win, though, a 41-10 win over Colgate. They have since lost to USC, Washington, Oregon and most recently Oregon State, a brutal 28-27 loss.

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Stanford at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:30 a.m. ET.

  • Moneyline (ML): Off the board.
  • Against the spread (ATS): Stanford +15.5 (-112) | Notre Dame -15.5 (-108)
  • Over/Under (O/U): 52.5 (O: -108 | U: -112)

2022 betting stats

  • ML: Stanford 1-4 | Notre Dame 3-2
  • ATS: Stanford 1-4 | Notre Dame 3-2
  • O/U: Stanford 3-1-1 | Notre Dame 1-4

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Stanford at Notre Dame head-to-head

The matchups between these 2 teams started almost a century ago in 1925. The Cardinals are 13-22 in the 35 games. They took an ugly loss in 2021, allowing 45 points and ultimately losing 45-14.

Stanford’s longest win streak is 3 while Notre Dame’s is 7. Stanford has lost 3 in a row and is largely expected to make it 4 in a row. The last time the Cardinals beat the Fighting Irish in Indiana was in 2016.

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