The San Francisco 49ers (9-4) and Seattle Seahawks (7-6) clash on Thursday Night Football in Week 15. Kickoff from Lumen Field will be at 8:15 p.m. ET (Prime Video). Below, we look at 49ers vs. Seahawks odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
San Francisco defeated the Tampa Bay Buccaneers 35-7 Sunday. The victory marked the 49ers’ 6th in a row straight up and 4th in a row against the spread (ATS). San Francisco has scored 33 or more points in 3 of its last 4 games.
The Seahawks were favored by 3.5 points Sunday against the Carolina Panthers, but lost 30-24, losing their 4th straight ATS. Seattle was held to 287 total yards Sunday and has logged fewer than 300 yards in 3 of their last 6 games.
Also see: All Week 15 odds and lines
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49ers at Seahawks odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:52 a.m. ET.
- Moneyline: 49ers -190 (bet $190 to win $100) | Seahawks +160 (bet $100 to win $160)
- Against the spread (ATS): 49ers -3.5 (-108) | Seahawks +3.5 (-112)
- Over/Under (O/U): 43.5 (O: -112 | U: -108)
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2022 betting stats
- ML: 49ers 9-4 | Seahawks 7-6
- ATS: 49ers 8-5 | Seahawks 6-7
- O/U: 49ers 6-7 | Seahawks 8-5
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49ers vs. Seahawks head-to-head
Seattle leads this 48-game all-time series 30-18. The ‘Niners defeated the Seahawks 27-17 earlier this season (Sept. 18), and that snapped a 4-game series win streak for the Seattle side.
Since 2012, the Seahawks are 12-1 at home in this series. Overall, 6 of the last 8 San Francisco-Seattle games have been decided by 1 score with the last 6 meetings netting a 3-3 ATS split.
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