The No. 5 Ohio State Buckeyes (5-1, 3-0 Big Ten) and Indiana Hoosiers (2-4, 0-3) are lined up for a Big Ten East Division battle Saturday night in Bloomington, Ind. Kickoff at Memorial Stadium is slated for 7:30 p.m. Below, we look at the Ohio State vs. Indiana odds and lines; check back for our college football picks and predictions.
Rankings courtesy the AFCA Coaches Poll powered by USA TODAY Sports.
Ohio State is coming off a bye week and enters this game having won four in a row. OSU has outscored its opponents, 218-57, over those four wins. With first-year QB C.J. Stroud finding his stride the Buckeyes have upped their season passing rank to ninth nationally (352.2 yards per game). Ohio State leads the nation in total yards (562.7 per game).
The Hoosiers lost 20-15 at home to Michigan State last week in a defensive struggle that featured less than 600 yards of offense. The Spartans had four scoring drives in the game; all four were shorter than 65 yards. IU ranks 108th in the nation with 340 total yards per game.
Ohio State at Indiana odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 3 p.m. ET.
- Money line: Ohio State -1000 (bet $1000 to win $100) | Indiana +600 (bet $100 to win $600)
- Against the spread (ATS): Ohio State -19.5, -115 (bet $115 to win $100) | Indiana +19.5, -105 (bet $105 to win $100)
- Over/Under (O/U): 60.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)
Also see: Betting 101
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2021 betting stats:
- ML: Ohio State 5-1 | Indiana 2-4
- ATS: Ohio State 3-2-1 | Indiana 1-5
- O/U: Ohio State 4-2 | Indiana 3-3
Ohio State at Indiana head-to-head
Indiana’s last win against Ohio State was in 1988. In 93 all-time meetings, the Buckeyes are 76-12-5 against the Hoosiers.
That includes in Nov. 2020 when OSU downed Indiana 42-35. The Bucks led that game 35-7 at the 11-minute mark of the second half.
Ohio State is 2-8 ATS in the last 10 meetings.
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