The No. 7 Notre Dame Fighting Irish (8-1, Independent) meet the Virginia Cavaliers (6-3, 4-2 ACC) at Scott Stadium in Charlottesville, Va. Kickoff is scheduled for 7:30 p.m. ET. Below, we look at the Notre Dame vs. Virginia odds and lines; check back for our college football picks and predictions.
The Fighting Irish posted a 34-6 victory over rival Navy last week, covering a 21-point number as the Under connected. The Irish has won and covered four in a row since its only loss of the season Oct. 2 vs. Cincinnati.
The Cavaliers were outscored 66-49 at BYU, Oct. 30, before the bye. Virginia has scored 48 or more points in three straight games, but lost QB Brennan Armstrong due to a rib injury in the fourth quarter vs. BYU. He is a question mark for this one.
Rankings according to the AFCA Coaches Poll powered by USA TODAY Sports.
Notre Dame at Virginia odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 7:50 a.m. ET.
- Money line: Notre Dame -205 (bet $205 to win $100) | Virginia +165 (bet $100 to win $165)
- Against the spread (ATS): Notre Dame -4.5, -112 (bet $112 to win $100) | Virginia +4.5, -108 (bet $108 to win $100)
- Over/Under (O/U): 64.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)
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2021 betting stats:
- ML: Notre Dame 8-1 | Virginia 6-3
- ATS: Notre Dame 6-3 | Virginia 6-3
- O/U: Notre Dame 5-4 | Virginia 3-6
Notre Dame at Virginia head-to-head
The Fighting Irish leads the all-time series 3-0 over the Cavaliers, including the most recent meeting Sept. 28, 2019. In the only previous meeting in Charlottesville, UVA picked up a 34-27 Sept. 12, 2015.
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