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The No. 17 Louisville Cardinals (3-0) take on the No. 14 Notre Dame Fighting Irish (3-1) Saturday at Notre Dame Stadium. Kickoff for is set for 3:30 p.m. (Peacock). Below, we look at Louisville vs. Notre Dame odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.
Louisville prevailed 31-19 against Georgia Tech Saturday, covering as a 9.5-point home favorite. QB Tyler Shough was 13-for-19 for 269 yards with 2 TDs and 0 interceptions. The Cardinals only managed 57 yards on the ground on 27 rushes, but 2 defensive touchdowns were paramount.
Notre Dame took down the Miami (Ohio) RedHawks 28-3 last week. The Irish dropped to 2-2 against the spread (ATS) after failing to cover as 27-point home favorites. They are 0-2 ATS when favored by more than 7 points. RB Riley Leonard finished with 143 rushing yards with 2 TDs on 12 carries.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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Louisville at Notre Dame odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Tuesday at 2:26 a.m. ET.
- Moneyline (ML): Louisville +185 (bet $100 to win $185) | Notre Dame -225 (bet $225 to win $100)
- Against the spread: Louisville +6 (-110) | Notre Dame -6 (-110)
- Over/Under (O/U): 48.5 (O: -110 | U: -110)
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2024 betting stats
- ML: Louisville 3-0 | Notre Dame 3-1
- ATS: Louisville 3-0 | Notre Dame 2-2
- O/U: Louisville 2-1 | Notre Dame 1-3
Louisville at Notre Dame head-to-head
The all-time series is tied 2-2. Louisville won the 1st meeting 31-28 as a 3-point underdog in South Bend in 2014, a year after Louisville moved to the ACC.
While the series is tied, Louisville is 4-0 ATS in all 4 games.
The Cardinals took the last matchup 33-20, covering as 6-point home dogs Oct. 3, 2023. The Cardinals held the Irish to just 44 yards on the ground while rushing for 185 yards themselves in that win.
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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