First look: Los Angeles Rams at Indianapolis Colts odds and lines

Looking at Sunday’s Los Angeles Rams at Indianapolis Colts Week 4 NFL odds, lines and trends. Here’s what you need to know.

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The Los Angeles Rams (1-2) and Indianapolis Colts (2-1) will square off in Week 4 on Sunday afternoon at Lucas Oil Stadium in Indianapolis. Kickoff  is set for 1 p.m. ET (FOX). Below, we look at Rams vs. Colts odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Rams lost at the Cincinnati Bengals 19-16 on Monday night to wrap up Week 3. They’ve now lost 2 straight after beating the Seattle Seahawks in the opener, dropping into a tie with the Arizona Cardinals for last in the NFC West.

The Colts stunned the Baltimore Ravens 22-19 in overtime on Sunday afternoon. Indianapolis is now 2-1 on the year, exceeding early expectations thus far despite being without QB Anthony Richardson for the last game and a half after he suffered a concussion. QB Gardner Minshew II stepped in and went 27 of 44 for 227 yards and a TD.

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Rams at Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 10:56 a.m. ET.

  • Moneyline (ML): Rams -105 (bet $105 to win $100) | Colts -115 (bet $115 to win $100)
  • Against the spread (ATS): Rams +1 (-110) | Colts -1 (-110)
  • Over/Under (O/U): 44.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Rams 1-2 | Colts 2-1
  • ATS: Rams 2-0-1 | Colts 2-1
  • O/U: Rams 1-2 | Colts 2-1

Rams vs. Colts head-to-head

Being in separate conferences, the Rams and Colts have only met 4 times since 2009. The Rams are 3-1 straight-up in that span, winning each of the last 3 meetings. The teams have split the series 2-2 straight up and against the spread, and the total has gone Over in each of the last 4 games.

One team has scored at least 38 points in 3 of their last 4 meetings, while their last matchup was a 27-24 win by the Rams in 2021.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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