First look: Iowa State at Iowa odds and lines

Looking at Saturday’s Iowa State Cyclones at Iowa Hawkeyes college football odds, lines and trends. Here’s what you need to know.

The Iowa State Cyclones (1-0) and Iowa Hawkeyes (1-0) tangle for the 69th time Saturday at 4 p.m. ET (BTN) at Kinnick Stadium in Iowa City, Iowa. Below, we analyze Tipico Sportsbook‘s lines around the Iowa State vs. Iowa odds; check back for our college football picks and predictions.

Iowa State defeated FCS Southeast Missouri State 42-10 Saturday. The Cyclones racked up 293 passing yards and 176 rushing yards. ISU had 26 first downs, a total it surpassed in just 2 of its games in 2021.

Iowa struggled its way to 166 total yards in defeating South Dakota State 7-3 Saturday. In a game that saw its combatants combine to go just 7-of-34 in converting 3rd downs, the Hawkeyes survived with not 1, but 2 safeties in emerging with a victorious baseball tally.

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Iowa State at Iowa odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:37 a.m. ET.

  • Money line: Iowa State +145 (bet $100 to win $145) | Iowa -170 (bet $170 to win $100)
  • Against the spread (ATS): Iowa State +3.5 (-120) | Iowa -3.5 (+100)
  • Over/Under (O/U): 41.5 (O: -103 | U: -117)

2022 betting stats:

  • ML: Iowa State 1-0 | Iowa 1-0
  • ATS: Iowa State 0-1 | Iowa 0-1
  • O/U: Iowa State 0-1 | Iowa 0-1

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Iowa State vs. Iowa head-to-head

The Hawkeyes lead the all-time in-state series — a battle for the Cy-Hawk Trophy — 46-22. Iowa won last year’s meeting 27-17 and is 6-0 against the Cyclones since 2015. Against the number, Iowa has won 4 of those 6 games.

ISU’s last win in Iowa City came in 2012.

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