First look: Indianapolis Colts at Houston Texans odds and lines

Looking at Indianapolis Colts at Houston Texans Week 1 NFL odds, lines and trends. Here’s what you need to know.

The Indianapolis Colts and Houston Texans meet in a Week 1 opener at NRG Stadium. Their Sept. 11 game will kick off at 1 p.m. (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Texans odds and lines; check back for our NFL picks and predictions.

The Colts last year went 6-1 from Nov. 4-Dec. 25, and they were 9-6 heading into the season’s final fortnight. But Indianapolis lost its final 2 games and missed the playoffs. The 2021 Colts’ rushing game (149.4 yards per game) ranked 2nd in the NFL.

The Texans struggled mightily in running the football (83.6 YPG, 32nd) en route to logging a 4-13 mark last season. Houston was tabbed as an underdog in 16 of its 17 games.

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Colts at Texans odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Aug. 29 at 11:04  a.m. ET.

  • Money line: Colts -410 (bet $100 to win $410) | Texans +310 (bet $310 to win $100)
  • Against the spread (ATS): Colts -7.5 (-112) | Texans +7.5 (-108)
  • Over/Under (O/U): 43.5 (O: -115 | U: -105)

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2021 betting stats:

  • ML: Colts 9-8 | Texans 4-13
  • ATS: Colts 10-7 | Texans 8-9
  • O/U: Colts 8-9 | Texans 8-9

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Colts vs. Texans head-to-head

Indianapolis swept 2 games from Houston last season by scores of 31-3 and 31-0. In an all-time series that dates back to 2002, Indy is 32-9 against the Texans.

Also see: All Week 1 odds and lines

Against the number, the Colts are 7-1 in their last 8 against the Texans. The last 5 games of the series have landed as Unders.

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