First look: Indiana at Ohio State odds and lines

Looking at Saturday’s Indiana at Ohio State college football odds, lines and trends. Here’s what you need to know.

The Indiana Hoosiers (3-6, 1-5 Big Ten) and No. 2 Ohio State Buckeyes (9-0, 6-0) meet Saturday at Ohio Stadium in Columbus. Kickoff is scheduled for noon ET (FOX). Below, we look at Indiana vs. Ohio State odds from Tipico Sportsbook; check back for all our college football picks and predictions.

The Hoosiers took it on the chin against Penn State at home, falling 45-14 at “The Rock” in Bloomington. After a 3-0 SU start, IU has now dropped its past 6 games, and bowl eligibility will not be possible unless it wins out.

The Buckeyes traveled to Northwestern last week and really struggled with winds blowing anywhere from 35-45 mph. The pass game was virtually non-existent, and Heisman Trophy candidate QB C.J. Stroud actually had more rushing yards than passing yards in the surprisingly narrow 21-7 win over the 1-win Wildcats.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

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Indiana at Ohio State odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:50 a.m. ET.

  • Moneyline (ML): Off the board
  • Against the spread (ATS): Indiana +41 (-112) | Ohio State -41 (-108)
  • Over/Under (O/U): 57.5 (O: -110 | U: -110)

2022 betting stats

  • ML: Indiana 3-6 | Ohio State 9-0
  • ATS: Indiana 3-6 | Ohio State 4-4-1
  • O/U: Indiana 5-4 | Ohio State 6-3

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Indiana at Ohio State head-to-head

The Buckeyes led the all-time series 77-12-5, including each of the previous 26 meetings dating back to 1991. The Hoosiers posted a 27-27 tie in the 1990 meeting, and the last time IU won outright was 41-7 in Bloomington back on Oct. 8, 1988. It hasn’t won in Columbus since Oct. 10, 1987, and that is the only win for the Hoosiers on the road in this series since 1951.

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