Denver Broncos at Los Angeles Chargers odds, picks and predictions

Analyzing Monday’s Denver Broncos at Los Angeles Chargers odds and lines, with expert NFL picks, predictions and best bets.

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The Denver Broncos (2-3) head to SoFi Stadium in Week 6 to face the Los Angeles Chargers (3-2) on Monday Night Football (ESPN). Kickoff is scheduled for 8:15 p.m. ET. Below, we analyze Tipico Sportsbook‘s lines around the Broncos vs. Chargers odds, and make our expert NFL picks and predictions.

The Broncos fell at home in Week 5 to the Indianapolis Colts 12-9 in OT on Thursday Night Football, so they should be well-rested. QB Russell Wilson completed 21 of 39 passes for 279 yards with 2 picks, finishing with a dismal 15.9 QBR (quarterback rating). WR Courtland Sutton led Denver’s receivers with 5 receptions for 74 yards – thanks to a 51-yard completion. On defense, S Caden Sterns led the way with 2 INTs.

In the end, it was play-calling decisions that largely hurt Denver. Once throwing an INT on 3rd down in the red zone and another when failing to convert on 4th down in OT, which put Indy in a great position to win the game.

The Chargers won at the Cleveland Browns 30-28 in Week 5 – Browns K Cade York missed a 54-yard FG attempt with 11 seconds remaining which likely would have won it. Chargers QB Justin Herbert went 22 of 34 for 228 yards and a TD, but it was RB Austin Ekeler who stole the show. Ekeler ran for 173 yards and a TD on 16 carries. RB Joshua Kelley (10/49/1) also had a good day on the ground.

The LA offense went 2 of 5 on red-zone opportunities. In order to find success through the rest of the season, it must improve on that metric.

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Broncos at Chargers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 6:03 p.m. ET.

  • Moneyline (ML): Broncos +180 (bet $100 to win $180) | Chargers -220 (bet $220 to win $100)
  • Against the spread (ATS): Broncos +4.5 (-110) | Chargers -4.5 (-110)
  • Over/Under (O/U): 45.5 (O: -108 | U: -112)

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Broncos at Chargers key injuries

Broncos

  • RB Melvin Gordon (neck, ribs) questionable
  • LB Josey Jewell (knee) out
  • DB Damarri Mathis (knee) questionable
  • OL Dalton Risner (back) questionable
  • TE Eric Saubert (thigh) questionable
  • Caden Sterns (hip) out

Chargers

  • WR Keenan Allen (hamstring) doubtful
  • Dustin Hopkins (right quadricep) LP
  • OL Trey Pipkins (knee) questionable

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Broncos at Chargers picks and predictions

Prediction

Chargers 31, Broncos 13

Moneyline

PASS.

Los Angeles’ odds (-220) are risky because they do not present as much return, but the Chargers should handle business at home. With the Broncos’ Wilson coming off a shoulder operation earlier this week, expect another lethargic game from the Denver offense, while Herbert and the Chargers offense should move easily Monday night.

But I can’t justify suggesting a -220 favorite. Let’s focus on the spread below.

Against the spread

BET CHARGERS -4.5 (-112).

The Chargers are 4-1 ATS in their last 5 games, while the Broncos are 1-4 in that same span. Plus, Denver is 0-5 ATS in its last 5 games on the road.

Still looking for their groove with Wilson, the Broncos have a lot of questions to be answered before they can confidently be backed.

Over/Under

TAKE UNDER 45.5 (-108). With a slow-moving, run-heavy Denver offense, the O/U line will be carried by Los Angeles. Although Herbert and company are capable of putting up big numbers, the only way the Over will hit is if Denver is able to find the end zone which does not seem likely. The Under is 4-1 this season in 5 Broncos games.

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