Cleveland Guardians at Minnesota Twins odds, picks and predictions

Analyzing Friday’s Cleveland Guardians at Minnesota Twins odds and lines, with MLB expert picks and predictions.

The Cleveland Guardians (25-31) and Minnesota Twins (30-27) clash in an AL Central showdown Friday in Minneapolis. First pitch at Target Field is slated for 8:10 p.m. ET (Apple TV+). Let’s analyze FanDuel Sportsbook’s lines around the Guardians vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: Twins lead 1-0

Cleveland lost Thursday’s series opener 7-6. The Guardians led 6-3 going into the bottom of the 8th, but Minnesota scored 3 runs in the 8th and a game-winner in the 9th. Cleveland is 3-9 over its last 12 road games.

The Minnesota offense has been feast or famine recently. The Twins have scored 7 or more runs 5 times and 1 run or fewer 3 times in their last 8 games.

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Guardians at Twins projected starters

RHP Aaron Civale vs. RHP Bailey Ober

Civale (1-1, 2.84 ERA) makes his 3rd start. He has a 1.03 WHIP, 1.4 BB/9 and 5.7 K/9 through 12 2/3 IP.

  • Returning from an oblique strain and a lengthy stay on the IL
  • Last pitched in an MLB game on April 7: 5 2/3 IP, 4 ER, 9 H, 1 BB, 5 K vs. the Seattle Mariners
  • Owns a 5.14 ERA over his last 5 starts against Minnesota (2020-22)

Ober (3-2, 2.68 ERA) makes his 8th start. He owns a 1.02 WHIP, 2.5 BB/9 and 8.3 K/9 through 40 1/3 IP.

  • Has held current Cleveland batters to an aggregate .157/.189/.196 (.385 OPS) line
  • Started the season at Triple-A and made his season debut on April 23
  • Has benefited from a .257 batting average on balls in play (BABIP) and a low 5.1% home runs/fly balls (HR/FB) mark

Guardians at Twins odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:53 a.m. ET.

  • Moneyline: Guardians +114 (bet $100 to win $114) | Twins -134 (bet $134 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians +1.5 (-184) | Twins -1.5 (+152)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Guardians at Twins picks and predictions

Prediction

Twins 6, Guardians 4

Moneyline

Take the baselines for the starting pitchers, add in some gray area for the Civale return — a plus for the Minnesota offense — and a couple of percentage ticks for the home side, and the lines here are tough to parse.

PASS.

Run line/Against the spread

Take the ML commentary and add extra juice: AVOID.

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Over/Under

The Over is 5-2 in the last 7 series meetings in Minnesota.

The Twins’ offense has been average thus far, but Minnesota has been awful in high-leverage situations in part due to a .259 BABIP in those spots. With solid home numbers (.773 OPS), it’s not a reach to consider Minnesota to be a top-10 offense in waiting.

Civale is a talented hurler, but what Cleveland gets out of him in this return is a question mark, and Ober is too far out over his skis with his surface ERA. Both bullpens are outperforming their numbers too, and the Guardians’ relief corps — at least at the back end — is not set up well after being used in trying to nurse a lead on Thursday.

On a warm evening in Minneapolis, BACK THE OVER 8.5 (-105).

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