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The Cleveland Guardians (6-2) and Minnesota Twins (3-3) play the middle contest of a 3-game series Saturday at Target Field after a scheduled day off. First pitch is scheduled for 2:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Twins odds and make our expert MLB picks and predictions for the best bets.
Season series: Guardians lead 1-0; Cleveland spoiled the home opener for Minnesota Thursday, winning 4-2 as an underdog (+150) as the Under (7) cashed
The Guardians have won 3 in a row, each as underdogs, and Cleveland has won 6 of 8 games on the road to open the season. The Under cashed on Thursday in the series opener, which was a rarity, as the Guardians had cashed the Over at a 5-1-1 pace in the 1st 7 games.
The Twins have dropped 3 of the past 4 games after opening 2-0. Minnesota is just 2-2 as a favorite, and the Under holds a 4-2 advantage in 6 games to date. Minnesota has scored 2 or fewer runs in 3 of the previous 4 outings, including an 11-0 shutout loss in Kansas City March 31.
Guardians at Twins projected starters
RHP Carlos Carrasco vs. RHP Joe Ryan
Carrasco (0-0, 5.40 ERA) makes his 2nd start in 2024. He allowed 3 ER on 6 H and 1 BB with 3 K in 5 IP in his debut at the Oakland Athletics Sunday.
- 2023 road splits (with the Mets): 2-5, 5.44 ERA (49 2/3 IP, 30 ER — 10 HR), 18 BB, 30 K in 10 starts
- Last start vs. Twins: Loss, 6 IP, 3 ER, 6 H, 1 BB, 5 K in 3-0 loss at Target Field Aug. 1, 2020, in 1st stint with Guardians
Ryan (0-0, 1.69 ERA) makes his 2nd start in 2024. He allowed 1 ER on 3 H and 1 BB with 5 K in 5 1/3 IP in his debut at the Kansas City Royals last Saturday.
- 2023 home splits: 7-4, 3.83 ERA (82 1/3 IP, 35 ER — 12 HR), 15 BB, 111 K in 14 starts
- 2023 vs. Guardians: 0-3, 3.24 ERA (16 2/3 IP, 6 ER — 0 HR), 2 BB, 11 K in 3 starts
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Guardians at Twins odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:45 a.m. ET.
- Moneyline (ML): Guardians +140 (bet $100 to win $140) | Twins -165 (bet $165 to win $100)
- Run line (RL)/Against the spread (ATS): Guardians +1.5 (-140) | Twins -1.5 (+115)
- Over/Under (O/U): 8.5 (O: -110 | U: -110)
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Guardians at Twins picks and predictions
Prediction
Guardians 4, Twins 3
Moneyline
The GUARDIANS (+140) are worth a look as moderate underdogs in the middle game of this set.
Last season, Ryan struggled against Cleveland, going 0-3 despite the fact he had a decent ERA at 3.24 in the 3 outings. However, the Twins (-165) have struggled against Cleveland in recent seasons, going just 3-6 in the past 9 meetings. They’re not worth playing as rather heavy favorites. Keep fading Minnesota until it starts beating Cleveland on the regular.
Run line/Against the spread
The GUARDIANS +1.5 (-140) aren’t priced out of line if you’re looking for a little insurance, and you just cannot trust the Twins -1.5 (+115).
As an underdog, Cleveland has posted a 4-1 mark in the past 5 on the run line, including 4 outright victories.
Over/Under
UNDER 8.5 (-110) cashed in the series opener Thursday while going 4-2 in the past 6 meetings and 7-3 across the past 10 battles in this series.
Cleveland’s pitching has been sharp so far, allowing 4 or fewer runs in 7 of 8 games, while allowing just 4 total runs in the previous 3 outings.
For Minnesota, it has scored just 2 or fewer runs in 3 of the past 4 outings, and Twins pitching has yielded just 4 runs or fewer in 5 of 6 games to date.
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